Results 21 to 30 of about 28,500 (228)
Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions [PDF]
, 2015 A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone.
A Andreoli +75 more
core +5 more sources
Soluble thrombomodulin activity and soluble thrombomodulin antigen in plasma [PDF]
Journal of Thrombosis and Haemostasis, 2005 Endothelial cell membrane-bound thrombomodulin (TM) plays a critical role as a cofactor in the protein C pathway, important in regulating coagulation as well as inflammation. Heterogeneous soluble TM fragments circulate in the plasma and are found at increased levels in various diseases such as cardiovascular disease and diabetes, and in ischemic and ...
A-K, Ohlin, K, Larsson, M, Hansson
openaire +2 more sources
Evaluation of thrombomodulin and pentraxin-3 as diagnostic biomarkers in calves with sepsis
Veterinární Medicína, 2018 Early diagnosis and treatment of sepsis in patients are crucial for their survival and can help reduce mortality rates. Novel biomarkers, such as thrombomodulin and pentraxin-3, have been used as diagnostic, prognostic and mortality indicators in ...
O. Aygun, R. Yildiz
doaj +1 more source
Biomedicines, 2022 Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and it is anticipated that it could become even more prevalent in parallel with an increase in the incidence of metabolic diseases closely related to NAFLD, such as ...
Armando Tripodi +5 more
doaj +1 more source
Medicina, 2019 Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is an acute respiratory worsening of unidentifiable cause that sometimes develops during the clinical course of IPF. Although the incidence of AE-IPF is not high, prognosis is poor.
Takuma Isshiki +2 more
doaj +1 more source
Haematologica, 2020 The bone marrow of patients with low-risk myelodysplastic syndromes (MDS) is often an inflammatory environment and associated with an active cellular immune response.
Nathalie van Leeuwen-Kerkhoff +5 more
doaj +1 more source
Potential benefits and risks of clinical xenotransplantation [PDF]
, 2012 The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core +2 more sources
Frontiers in Cardiovascular Medicine, 2022 A young man repeatedly found a right atrial mass with severe wheezing and extreme dyspnea. His condition was critical and complicated. The process of correct diagnosis was full of twists and turns.
Huarui Wang +4 more
doaj +1 more source
Limited Ability to Activate Protein C Confers Left Atrial Endocardium A Thrombogenic Phenotype: A Role in Cardioembolic Stroke? [PDF]
, 2011 Background and Purpose—Atrial fibrillation is the most important risk factor for cardioembolic stroke. Thrombi form in the left atrial appendage rather than in the right. The causes of this different thrombogenicity are not well-understood.
Cervero, J. (Jorge) +4 more
core +1 more source
Frontiers in Immunology, 2023 Lupus nephritis (LN) is a common and severe manifestation of systemic lupus erythematosus and an important cause of acute and chronic kidney injury. Early diagnosis of LN and preventing relapses are key to preserving renal reserve.
Susan Yung, Tak Mao Chan
doaj +1 more source