Results 31 to 40 of about 17,882 (212)

Assessment of Serum Thrombomodulin in Patients with Systemic Lupus Erythematosus in Rheumatology Research Center [PDF]

Acta Medica Iranica, 2009
At present, some clinical presentations and serological parameters such as products of complement activation and elevation of autoantibodies (e.g. dsDNA antibodies), erythrocyte sedimentation rate (ESR), levels of C-reactive protein (CRP), or cytokines ...
Mahmood Akbarian, Farhad Gharibdoost, Mehrzad Hadjaliloo, Abdolhadi Nadji, Ahmad Reza Jamshidi, Farhad Shahram, Masoomeh Akhlaghi, Shahrzad Khosravi, Simin Almasi, Fereydoun Davatchi   +9 more
doaj   +1 more source

Human Thrombomodulin Knock-In Mice Reveal Differential Effects of Human Thrombomodulin on Thrombosis and Atherosclerosis [PDF]

, 2011
Objective— We sought to develop a murine model to examine the antithrombotic and antiinflammatory functions of human thrombomodulin in vivo.
Stevens, J. W., Lorie Leo, Wilder, J., Erger, R. A., Griffin, J. H., Fernandez, J. A., Hyung-Suk Kim, Jose A. Fernández, Dwyre, D. M., Nobuyo Maeda, Jennifer Wilder, Maeda, N., John H. Griffin, Leo, L., Denis M. Dwyre, Jeff W. Stevens, Kim, H.-S., Raife, T. J., Thomas J. Raife, Rochelle A. Erger, Steven R. Lentz, Wilson, K. M., Lentz, S. R., Katina M. Wilson   +23 more
core   +1 more source

Increased serum thrombomodulin level is associated with disease severity and mortality in pediatric sepsis.

PLoS ONE, 2017
BackgroundEndothelial dysfunction plays an important role in the pathophysiology of sepsis. As previously reported, the serum thrombomodulin is elevated in diseases associated with endothelial injury.ObjectiveThe aim of this study was to investigate the ...
Jainn-Jim Lin, Hsiang-Ju Hsiao, Oi-Wa Chan, Yu Wang, Shao-Hsuan Hsia, Cheng-Hsun Chiu   +5 more
doaj   +1 more source

Thrombomodulin Levels in Umbilical Cord Blood-derived Plasma between Light-for-Date and Appropriate-for-Date Infants [PDF]

, 2018
Thrombomodulin, a thrombin receptor on the surface of endothelial cells, plays an important role not only in maintaining normal hemostatic balance but also in in utero development.
Kinoshita, Fumiko, Masuzaki, Hideaki, Miyamura, Tsunetake, Funakoshi, Yasutomo, Okada, Masahiko, Aoki, Mikihiro, Moriuchi, Hiroyuki   +6 more
core   +1 more source

Loss of placental thrombomodulin in oocyte donation pregnancies [PDF]

, 2017
Objective To investigate whether thrombomodulin dysregulation is involved in the development of preeclampsia after oocyte donation (OD). Women who become pregnant after OD are prone to develop preeclampsia, a syndrome characterized by an aberrant ...
Bruijn, Jan A., Baelde, Hans J., Turner, Rosanne J., Bos, Manon, Bloemenkamp, Kitty W M, van der Hoorn, Marie Louise P   +5 more
core   +1 more source

Normal thrombin generation in neonates in spite of prolonged conventional coagulation tests

Haematologica, 2008
Conventional coagulation tests might be inadequate to explore mechanisms regulating thrombin generation in neonates, because they do not allow full activation of the reduced levels of protein C.
Armando Tripodi, Luca A. Ramenghi, Veena Chantarangkul, Agnese De Carli, Marigrazia Clerici, Michela Groppo, Fabio Mosca, Pier Mannuccio Mannucci   +7 more
doaj   +1 more source

Impact of Laparoscopic Sleeve Gastrectomy on Thrombomodulin Concentration and Early Markers of Atherosclerosis

Journal of Interventional Cardiology, 2022
Background. Thrombomodulin, an integral membrane protein functioning as a cofactor in the anticoagulant pathways, has recently emerged as a marker of endothelial dysfunction.
Hasan Elkan, Mehmet Memduh Baş, Berna Kaya   +2 more
doaj   +1 more source

Biomarkers in Patients with Hand-Arm Vibration Injury Entailing Raynaud’s Phenomenon and Cold Sensitivity, Compared to Referents

Proceedings, 2023
The clinical evaluation of patients with neurosensory injury is based on quantitative sensory testing. Such tests require the patient’s cooperation, which may sometimes hinder a correct diagnosis.
Eva Tekavec, Tohr Nilsson, Lars B. Dahlin, Anna Axmon, Catarina Nordander, Jakob Riddar, Monica Kåredal   +6 more
doaj   +1 more source

High plasma thrombomodulin level is associated with a decreased risk of cognitive impairment after ischemic stroke

Journal of Stroke and Cerebrovascular Diseases
Background: Thrombomodulin, a thrombin receptor with anticoagulant, anti-inflammatory, and cytoprotective properties, has been suggested to play a pivotal role in ischemic stroke.
Yu He, MD, Xinyue Chang, MD, Yi Liu, MD, Jiawen Fei, MD, Xiaoli Qin, MD, Beiping Song, MD, Quan Yu, MD, Mengyao Shi, MD, PhD, Daoxia Guo, MD, PhD, Jing Chen, MD, MS, Aili Wang, MD, PhD, Tan Xu, MD, PhD, Jiang He, MD, PhD, Yonghong Zhang, MD, PhD, Zhengbao Zhu, MD, PhD   +14 more
doaj   +1 more source

Atypical hemolytic uremic syndrome

Orphanet Journal of Rare Diseases, 2011
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae
Frémeaux-Bacchi Véronique, Loirat Chantal   +1 more
doaj   +1 more source