Results 31 to 40 of about 16,590 (223)

Biomarkers in Patients with Hand-Arm Vibration Injury Entailing Raynaud’s Phenomenon and Cold Sensitivity, Compared to Referents

Proceedings, 2023
The clinical evaluation of patients with neurosensory injury is based on quantitative sensory testing. Such tests require the patient’s cooperation, which may sometimes hinder a correct diagnosis.
Eva Tekavec, Tohr Nilsson, Lars B. Dahlin, Anna Axmon, Catarina Nordander, Jakob Riddar, Monica Kåredal   +6 more
doaj   +1 more source

Thrombomodulin Production.

, 2013
Thrombomodulin expression from (A) proliferative and (B) quiescent SMCs in response to treatment with DS-SILY20. Thrombomodulin expression decreased with the addition low concentrations of DS-SILY20; however, the addition of either 1 or 10 μM DS-SILY20 ...
Alyssa Panitch (348401), John E. Paderi (488957), Michael Sturek (378773), Rebecca A. Scott (488956)   +3 more
core   +1 more source

Functional and Immunoreactive Thrombomodulin Expressed by Keratinocytes

, 1994
In an immunohistopathologic study using two monoclonal antibodies that recognize independent epitopes on human thrombomodulin, we detected expression of thrombomodulin on Malpighian-layer keratinocytes, but not on the basal or upper granular-layer ...
Hayashi, Tatsuya, Hashimoto, Koji, Shimizu, Masayuki, Ohyanagi, Satoshi, Nouchi, Nobuhiro, Mizutani, Hitoshi, Suzuki, Koji   +6 more
core   +1 more source

Endothelium-Mimetic Surface Modification Improves Antithrombogenicity and Enhances Patency of Vascular Grafts in Rats and Pigs

JACC: Basic to Translational Science, 2023
Summary: We first identified thrombomodulin (TM) and endothelial nitric oxide (NO) synthase as key factors for the antithrombogenic function of the endothelium in human atherosclerotic carotid arteries.
Yongzhen Wei, PhD, Huan Jiang, BS, Chao Chai, MD, Pei Liu, MS, Meng Qian, PhD, Na Sun, MD, Man Gao, MS, Honglin Zu, MD, Yongquan Yu, MD, Guangbo Ji, BS, Yating Zhang, BS, Sen Yang, MD, Ju He, MD, Jiansong Cheng, PhD, Jinwei Tian, MD, PhD, Qiang Zhao, PhD   +15 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Coagulation phenotypes in sepsis and effects of recombinant human thrombomodulin: an analysis of three multicentre observational studies

Critical Care, 2021
Background A recent randomised trial showed that recombinant thrombomodulin did not benefit patients who had sepsis with coagulopathy and organ dysfunction.
Daisuke Kudo, Tadahiro Goto, Ryo Uchimido, Mineji Hayakawa, Kazuma Yamakawa, Toshikazu Abe, Atsushi Shiraishi, Shigeki Kushimoto   +7 more
doaj   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Atypical hemolytic uremic syndrome

Orphanet Journal of Rare Diseases, 2011
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae
Frémeaux-Bacchi Véronique, Loirat Chantal   +1 more
doaj   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source