Results 41 to 50 of about 16,590 (223)

Multicenter Interlaboratory Study of Thrombin Generation Assay in Healthy Adults Using the ST Genesia Analyzer With the STG‐ThromboScreen Reagent (With and Without Thrombomodulin)

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Fully automated thrombin generation (TG) assays facilitate the transition from research to clinical application. We conducted a multicenter inter‐laboratory study using the ST Genesia analyzer to evaluate assay performance and establish reference intervals in healthy adults from Spain and Portugal.
Diego Velasco‐Rodríguez   +21 more
wiley   +1 more source

Human Thrombomodulin Knock-In Mice Reveal Differential Effects of Human Thrombomodulin on Thrombosis and Atherosclerosis

open access: yes, 2011
Objective— We sought to develop a murine model to examine the antithrombotic and antiinflammatory functions of human thrombomodulin in vivo.
Stevens, J. W.   +23 more
core   +1 more source

Serum thrombomodulin [PDF]

open access: yesArthritis & Rheumatism, 1994
AbstractObjective. Soluble thrombomodulin (sTM), a proposed serum marker of endothelial cell injury, was investigated as a parameter of disease activity in patients with systemic lupus erythematosus (SLE).Methods. Levels of sTM were determined by enzyme‐linked immunosorbent assay.
Michael W. J. Boehme   +7 more
openaire   +1 more source

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold   +9 more
wiley   +1 more source

Glomerular localization of thrombomodulin in human glomerulonephritis [PDF]

open access: yes, 1993
名古屋大学NAGOYA University博士(医学)名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成5年9月14日 水谷大裕氏の博士論文として提出されたdoctoral ...
丸山, 征郎   +9 more
core  

The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature

open access: yesNature Communications, 2019
The endothelium actively maintains an anticoagulant surface through expression of thrombomodulin. Here, Peghaire et al. identify an anti-thrombotic pathway that controls thrombomodulin expression selectively in regions of low shear stress, via ...
C. Peghaire   +13 more
doaj   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai   +7 more
wiley   +1 more source

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

open access: yesVIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda   +5 more
wiley   +1 more source

Thrombomodulin mutations in atypical hemolyticuremic syndrome

open access: yes, 2009
: Background The hemolyticuremic syndrome consists of the triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. The common form of the syndrome is triggered by infection with Shiga toxinproducing bacteria and has a favorable ...
Claes, Bart   +25 more
core   +1 more source

The Role of Thrombomodulin in Estrogen-Receptor-Positive Breast Cancer Progression, Metastasis, and Curcumin Sensitivity

open access: yesBiomedicines, 2023
Estrogen and estrogen receptors (ER) play a key role in breast cancer progression, which can be treated with endocrine therapy. Nevertheless, resistance to endocrine therapies is developed over time.
Chien-Yu Huang   +6 more
doaj   +1 more source

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