Results 61 to 70 of about 17,882 (212)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, Volume 4, Issue 3, September 2026.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Effect of dengue hemorrhagic fever on thrombomodulin level [PDF]

, 2009
Background Thrombocyte and endothelial cells play animportant role in dengue hemorrhagic fever pathogenesis.Thrombomodulin is a part of glycoprotein membrane inendothelial cells.
Hendra Widjaja, Max F. J. Mantik
core   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Regulation of Brain Capillary Endothelial Thrombomodulin mRNA Expression

, 1996
Background and Purpose Endothelial cells regulate hemostasis in part via expression of thrombomodulin, a potent anticoagulant protein.
Vicky L.Y. Wong, Mark Fisher, Nam D. Tran, Steven S. Schreiber, James V. Bready   +4 more
core   +1 more source

Reciprocal antagonism between inflammation and the protein C system

Romanian Journal of Laboratory Medicine, 2013
Proteina C, o protează serinică dependentă de vitamina K, sintetizată in hepatocite ca zimogen inactiv, se activează sub acţiunea trombinei în complex cu trombomodulina endotelială. Un receptor endotelial al proteinei C (EPCR) intervine atât în activarea
Cucuianu Mircea, Brudasca Ioana, Plesca Luminita, Bodizs Gyorgy, Colhon Dan, Cucuianu Andrei   +5 more
doaj   +1 more source

Cytokine‐Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies—A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Low Vitamin D Serum Level Is Associated with HDL-C Dyslipidemia and Increased Serum Thrombomodulin Levels of Insulin-Resistant Individuals

Diabetes, Metabolic Syndrome and Obesity, 2020
Fatemeh Saheb Sharif-Askari,1 Narjes Saheb Sharif-Askari,1 Rabih Halwani,1,2 Salah Abusnana,2,3 Rifat Hamoudi,1,2 Nabil Sulaiman1,4,5 1Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates ...
Saheb Sharif-Askari F, Saheb Sharif-Askari N, Halwani R, Abusnana S, Hamoudi R, Sulaiman N   +5 more
doaj  

Whole exome sequencing identifies a mutation in thrombomodulin as the genetic cause of a suspected platelet disorder in a family with normal platelet function

Platelets, 2017
Here, we describe a mother and son with a lifelong bleeding tendency and posttraumatic bleeding who were recruited to the UK Genotyping and Phenotyping of Platelets (GAPP) study with a suspected platelet function disorder.
Annabel Maclachlan, Gerry Dolan, Charlotte Grimley, Steve P. Watson, Neil V. Morgan, on behalf of the UK GAPP Study Group   +5 more
doaj   +1 more source

The correlations between thrombomodulin and various parameters.

, 2016
The correlations between thrombomodulin and various parameters.
Yoshinori Inoue (816495), Toshifumi Kudo (816494), Takahiro Toyofuku (3353303), Kimihiro Igari (3353300)   +3 more
core   +1 more source

Circulating thrombomodulin levels in familial mediterranean fever

, 2006
Increments in circulating thrombomodulin levels reflect endothelial cell injury. Thrombomodulin can also be synthesized by several inflammatory cells including monocytes, neutrophils, and thrombomodulin itself can modulate the inflammatory response.
Calguneri, Meral, Onat, A. Mesut, KİRAZ, SEDAT, Ozbalkan, Zeynep, Ureten, KEMAL, ERTENLİ, ALİ İHSAN, ÖZTÜRK, MEHMET AKİF, Kirazli, Serafettin, HAZNEDAROĞLU, İBRAHİM CELALETTİN   +8 more
core   +1 more source