Results 51 to 60 of about 16,590 (223)
Microcirculation, Volume 33, Issue 5, July 2026.ABSTRACT Objective This study investigated the relationship between sublingual microcirculatory tortuosity, frailty index scores, and endothelial glycocalyx blood biomarkers in individuals with chronic kidney disease (CKD). Methods Sublingual microcirculatory videos were analyzed using a 0–4 tortuosity scoring scale. Plasma concentrations of syndecan‐1
Ryan A. P. Homes +6 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundSepsis-associated acute kidney injury (SA-AKI) is a common complication of sepsis. Serum creatinine is a delayed AKI marker influenced by multiple confounders and cannot reflect endothelial injury central to SA-AKI.
Hao Hong +7 more
doaj +1 more source
Circulating concentrations of glycocalyx degradation products in preeclampsia
Frontiers in Physiology, 2022 Background and Objectives: Preeclampsia is a multisystem disorder that affects maternal endothelium. The glycocalyx lines and protects the endothelial surface.
Niclas Carlberg +13 more
doaj +1 more source
Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation
ACR Open Rheumatology, Volume 8, Issue 6, June 2026.Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley +1 more source
Thrombomodulin Regulation of Mitogen-Activated Protein Kinases
, 2019 The multifaceted role of mitogen-activated protein kinases (MAPKs) in modulating signal transduction pathways in inflammatory conditions such as infection, cardiovascular disease, and cancer has been well established.
Hemant Giri +4 more
core +1 more source
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Advanced Science, Volume 13, Issue 33, 15 June 2026.Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
Regulation of Brain Capillary Endothelial Thrombomodulin mRNA Expression
, 1996 Background and Purpose Endothelial cells regulate hemostasis in part via expression of thrombomodulin, a potent anticoagulant protein.
Vicky L.Y. Wong +4 more
core +1 more source
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, Volume 13, Issue 33, 15 June 2026.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Neonatal limb gangrene with auto‐amputation is rare and often idiopathic. Early recognition, prompt referral, and thorough etiologic workup—despite resource limitations—are critical. Wet gangrene requires broad‐spectrum antibiotics, wound care, and timely surgical amputation to preserve growth plates and allow future prosthesis fitting.
Milki Tufa Feyisa +7 more
wiley +1 more source
Loss of placental thrombomodulin in oocyte donation pregnancies
, 2017 Objective To investigate whether thrombomodulin dysregulation is involved in the development of preeclampsia after oocyte donation (OD). Women who become pregnant after OD are prone to develop preeclampsia, a syndrome characterized by an aberrant ...
Bruijn, Jan A. +5 more
core +1 more source