Results 51 to 60 of about 17,882 (212)
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic +3 more
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov +3 more
wiley +1 more source
Glomerular localization of thrombomodulin in human glomerulonephritis [PDF]
, 1993 名古屋大学NAGOYA University博士(医学)名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成5年9月14日 水谷大裕氏の博士論文として提出されたdoctoral ...
丸山, 征郎 +9 more
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Molecular Oral Microbiology, EarlyView.Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source
Thrombomodulin mutations in atypical hemolyticuremic syndrome
, 2009 : Background The hemolyticuremic syndrome consists of the triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. The common form of the syndrome is triggered by infection with Shiga toxinproducing bacteria and has a favorable ...
Claes, Bart +25 more
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Biomedicines, 2023 Estrogen and estrogen receptors (ER) play a key role in breast cancer progression, which can be treated with endocrine therapy. Nevertheless, resistance to endocrine therapies is developed over time.
Chien-Yu Huang +6 more
doaj +1 more source
Lung‐Cardiovascular Interactions and Derangements in ARDS
Comprehensive Physiology, Volume 16, Issue 5, October 2026.This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez +4 more
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Arthritis & Rheumatism, 1994 AbstractObjective. Soluble thrombomodulin (sTM), a proposed serum marker of endothelial cell injury, was investigated as a parameter of disease activity in patients with systemic lupus erythematosus (SLE).Methods. Levels of sTM were determined by enzyme‐linked immunosorbent assay.
Michael W. J. Boehme +7 more
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Obesity Reviews, Volume 27, Issue 10, October 2026.Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold +9 more
wiley +1 more source
Thrombomodulin Regulation of Mitogen-Activated Protein Kinases
, 2019 The multifaceted role of mitogen-activated protein kinases (MAPKs) in modulating signal transduction pathways in inflammatory conditions such as infection, cardiovascular disease, and cancer has been well established.
Hemant Giri +4 more
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