Results 21 to 30 of about 3,493 (184)
Dataset for characterization of thrombospondin family in chum salmon (Oncorhynchus keta)
Data in Brief, 2019 An extracellular matrix (ECM) is composed of multiprotein networks for stable interactions between cells. Thrombospondins (TSPs) are known to exert extracellular matrix interactions, synapse formation, angiogenesis and immune response in vertebrates.
Sang Yoon Lee, Yi Kyung Kim
doaj +1 more source
Cells, 2020 Astrocytes have critical functions throughout the central nervous system (CNS) and have emerged as regulators of synaptic development and function.
Christopher D. Walker +2 more
doaj +1 more source
Shaping Synapses by the Neural Extracellular Matrix
Frontiers in Neuroanatomy, 2018 Accumulating data support the importance of interactions between pre- and postsynaptic neuronal elements with astroglial processes and extracellular matrix (ECM) for formation and plasticity of chemical synapses, and thus validate the concept of a ...
Maura Ferrer-Ferrer +3 more
doaj +1 more source
Clinical and Experimental Hypertension, 2023 Background Thrombospondins (TSPs) play important roles in several cardiovascular diseases. However, the association between circulating (plasma) thrombospondin 2 (TSP2) and essential hypertension remains unclear.
Xiaoxin Zhou +11 more
doaj +1 more source
The Roles of Thrombospondins in Hemorrhagic Stroke [PDF]
, 2017 Hemorrhagic stroke is a devastating cerebrovascular disease with significant morbidity and mortality worldwide. Thrombospondins (TSPs), as matricellular proteins, belong to the TSP family which is comprised of five members. All TSPs modulate a variety of
Xuan Wu +7 more
core +1 more source
Frontiers in Physiology, 2014 Nitric oxide (NO) maintains cardiovascular health by activating soluble guanylate cyclase (sGC) to increase cellular cGMP levels. Cardiovascular disease is characterized by decreased NO-sGC-cGMP signaling.
Natasha M Rogers +4 more
doaj +1 more source
Regulation of bestrophins by Ca2+: a theoretical and experimental study. [PDF]
PLoS ONE, 2009 Bestrophins are a recently discovered family of Cl(-) channels, for which no structural information is available. Some family members are activated by increased intracellular Ca2+ concentration.
Agata Kranjc +7 more
doaj +1 more source
Diabetes and Retinal Vascular Dysfunction
Journal of Ophthalmic & Vision Research, 2014 Diabetes predominantly affects the microvascular circulation of the retina resulting in a range of structural changes unique to this tissue. These changes ultimately lead to altered permeability, hyperproliferation of endothelial cells and edema, and ...
Eui Seok Shin +2 more
doaj +1 more source
TP53 status is associated with thrombospondin1 expression in vitro
Frontiers in Oncology, 2013 Objectives: To elucidate the association between thrombospondin1 (THBS1) expression and TP53 status and THBS1 promoter methylation in epithelial ovarian cancer (EOC).
Angeles eAlvarez Secord +9 more
doaj +1 more source
The Interaction of Thrombospondins with Extracellular Matrix Proteins [PDF]
, 2009 The thrombospondins (TSPs) are a family of five matricellular proteins that appear to function as adapter molecules to guide extracellular matrix synthesis and tissue remodeling in a variety of normal and disease settings. Various TSPs have been shown to
Jack Lawler +3 more
core +1 more source