Results 21 to 30 of about 100,658 (276)

The Differential Diagnosis and Treatment of Thrombotic Microangiopathies. [PDF]

Dtsch Arztebl Int, 2018
Bommer M, Wölfle-Guter M, Bohl S, Kuchenbauer F.   +3 more
europepmc   +2 more sources

Immune-mediated thrombotic thrombocytopenic purpura plasma induces calcium- and IgG-dependent endothelial activation: correlations with disease severity

Haematologica, 2022
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by a severe ADAMTS13 deficiency due to the presence of anti-ADAMTS13 auto-antibodies, with subsequent accumulation of circulating ultra-large von Willebrand factor (VWF ...
Edwige Tellier, Agnès Widemann, Raphaël Cauchois, Julien Faccini, Marie Lagarde, Marion Brun, Philippe Robert, Stéphane Robert, Richard Bachelier, Pascale Poullin, Elien Roose, Karen Vanhoorelbeke, Paul Coppo, Françoise Dignat-George, Gilles Kaplanski   +14 more
doaj   +1 more source

A British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies

British Journal of Haematology, 2023
The objective of this guideline is to provide healthcare professionals with clear, up‐to‐date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement ...
M. Scully, R. Rayment, A. Clark, J. Westwood, T. Cranfield, R. Gooding, C. Bagot, A. Taylor, V. Sankar, D. Gale, T. Dutt, J. McIntyre, W. Lester   +12 more
semanticscholar   +1 more source

Epidemiology, Outcomes, and Complement Gene Variants in Secondary Thrombotic Microangiopathies

American Society of Nephrology. Clinical Journal, 2023
Visual Abstract Background The identification of complement defects as major drivers of primary atypical hemolytic uremic syndrome (HUS) has transformed the landscape of thrombotic microangiopathies (TMAs), leading to the development of targeted ...
A. Werion, P. Storms, Ysaline Zizi, C. Beguin, J. Bernards, J. Cambier, K. Dahan, D. Dierickx, N. Godefroid, P. Hilbert, C. Lambert, E. Levtchenko, Thomas Meyskens, X. Poiré, L. P. van den Heuvel, K. Claes, J. Morelle   +16 more
semanticscholar   +1 more source

Thrombotic microangiopathy coming of age [PDF]

, 2015
Ruiz Delgado, Guillermo José
core   +2 more sources

Thrombotic Microangiopathies [PDF]

ISRN Hematology, 2012
Thrombotic microangiopathy results from thrombotic occlusion of the microvasculature leading to fragmentation of red blood cells, profound thrombocytopenia, and a microangiopathic hemolytic anemia with elevation of lactate dehydrogenase and negative direct Coomb’s test.
Radhi, Mohamed, Carpenter, Shannon L.
openaire   +3 more sources

Physiopathological implications of abnormal Arterial Spin Labeling perfusion in thrombotic microangiopathy

Thrombosis Update, 2021
Thrombotic microangiopathies are a group of clinical syndromes characterized by microangiopathic hemolytic anemia, thrombocytopenia and end-organ damage, which can compromise the central nervous system.
Xavier Merchán-del-Hierro, María-Victoria Camino, Gabriel Persi, Carlos Rugilo, María-Pilar Sánchez-de-Paz, Emilia Gatto   +5 more
doaj   +1 more source

Thrombotic Thrombocytopenic Purpura as a Rare Etiopathogenetic Cause of Cerebral Infarction and Extracerebral Thrombosis

Вестник анестезиологии и реаниматологии, 2021
Thrombotic thrombocytopenic purpura is a disease from the group of thrombotic microangiopathies, the early diagnosis of which is a real challenge in clinical practice.
А. R. Аvidzba, V. A. Saskin, E. V. Nedashkovskiy   +2 more
doaj   +1 more source

COVID-19 and Thrombotic Thrombocytopenic Purpura: A Case Report

International Journal of Hematology-Oncology and Stem Cell Research, 2021
Endothelial injury by toxins, drugs, immune complexes leads to activation of coagulation cascade and thrombosis, which result in platelet consumption and red blood cell injury. These thrombotic microangiopathies can potentially injure numerous organs and
Maryam Darnahal, Hamed Azhdari Tehrani, Mohammad Vaezi, Shirin Haghighi   +3 more
doaj   +1 more source

Thrombotic microangiopathies postrenal transplantation

Indian Journal of Transplantation, 2020
Aims: The aim of the study was to describe 12 cases of thrombotic microangiopathy (TMA) postrenal transplantation and study the causes, treatment, and outcomes.
Kartik Ganesh, Abi M Abraham, Jithin S Kumar, Renu S Paul, Sunita Simon, Nirmal Harshan   +5 more
doaj   +1 more source