Results 21 to 30 of about 47,275 (224)

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]

, 2012
Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko (144194), Thiery, Joachim, Berthold Koletzko, Bruegel Mathias, Linda Kortz, Kiess Wieland, Beblo, Skadi, Kortz, Linda, Kortz Linda, Linda Kortz (144188), Wieland Kiess (102793), Uta Ceglarek (144203), Skadi Beblo (144186), Claudia Matthies (144191), Kiess, Wieland, Bruegel, Mathias, Mathias Bruegel (144197), Wieland Kiess, Beblo Skadi, Ulrike Mütze, Koletzko Berthold, Skadi Beblo, Ceglarek Uta, Ceglarek, Uta, Ulrike Mütze (144183), Joachim Thiery, Joachim Thiery (66414), Rohde, Carmen, Matthies, Claudia, Matthies Claudia, Rohde Carmen, Uta Ceglarek, Mütze, Ulrike, Koletzko, Berthold, Mathias Bruegel, Carmen Rohde, Carmen Rohde (144200), Thiery Joachim, Mütze Ulrike, Claudia Matthies   +39 more
core   +2 more sources

The antithrombosis effect of dehydroandrographolide succinate: in vitro and in vivo studies

Pharmaceutical Biology, 2022
Context Dehydroandrographolide succinate (DAS) is mainly used in the clinical treatment of various infectious diseases. Its potential effects on platelet aggregation and blood coagulation systems have not been reported systematically.
Bowen Yin, Shuhua Zhang, Yuxi Huang, Yuanzhu Long, Yiguo Chen, Shiyun Zhao, Aiqun Zhou, Minghua Cao, Xiaoming Yin, Daya Luo   +9 more
doaj   +1 more source

A monoclonal anti-thromboxane B2 antibody [PDF]

, 1988
A monoclonal antibody against thromboxane B2 which may be used in standard fluid phase radioimmunoassays with a detection limit of around 40 pg and a binding affinity of 1.98 × 109 M−1 is described.
Margot Reinke, Brune, Kay, Reinke, Margot, Kay Brune   +3 more
core   +1 more source

Targeting Platelet Activation Pathways to Limit Tumour Progression: Current State of Affairs

Pharmaceuticals, 2022
The association between cancer and a hypercoagulatory environment is well described. Thrombotic complications serve not only as a major mortality risk but the underlying molecular structure and function play significant roles in enhancing tumour ...
Kutlwano R. Xulu, Tanya N. Augustine
doaj   +1 more source

Thromboxanes: Synthase and Receptors

Journal of Biomedical Science, 1998
Thromboxane A2 is a biologically potent arachidonate metabolite through the cyclooxygenase pathway. It induces platelet aggregation and smooth muscle contraction and may promote mitogenesis and apoptosis of other cells. Its roles in physiological and pathological conditions have been widely documented.
R F, Shen, H H, Tai
openaire   +2 more sources

Thrombo-Inflammation in COVID-19 and Sickle Cell Disease: Two Faces of the Same Coin

Biomedicines, 2023
People with sickle cell disease (SCD) are at greater risk of severe illness and death from respiratory infections, including COVID-19, than people without SCD (Centers for Disease Control and Prevention, USA).
Kate Chander Chiang, Ajay Gupta, Prithu Sundd, Lakshmanan Krishnamurti   +3 more
doaj   +1 more source

Platelet-Derived Extracellular Vesicles as Target of Antiplatelet Agents. What Is the Evidence?

Frontiers in Pharmacology, 2019
Platelet-derived large extracellular vesicles (often referred to as microparticles in the field of cardiovascular disease) have been identified as effector in the atherothrombotic process, therefore representing a target of pharmacological intervention ...
Francesco Taus, Alessandra Meneguzzi, Marco Castelli, Pietro Minuz   +3 more
doaj   +1 more source

Effect of Polyphenols From Campomanesia adamantium on Platelet Aggregation and Inhibition of Cyclooxygenases: Molecular Docking and in Vitro Analysis

Frontiers in Pharmacology, 2018
Campomanesia adamantium is a medicinal plant of the Brazilian Cerrado. Different parts of its fruits are used in popular medicine to treat gastrointestinal disorders, rheumatism, urinary tract infections and inflammations.
Caroline H. Lescano, Fernando Freitas de Lima, Camila B. Mendes-Silvério, Alberto F. O. Justo, Débora da Silva Baldivia, Cristiano P. Vieira, Eliana J. Sanjinez-Argandoña, Claudia A. L. Cardoso, Fabíola Z. Mónica, Ivan Pires de Oliveira   +9 more
doaj   +1 more source

Isolated Human Pulmonary Artery Structure and Function Pre‐ and Post‐Cardiopulmonary Bypass Surgery

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundPulmonary dysfunction is a known complication after cardiac surgery using cardiopulmonary bypass, ranging from subclinical functional changes to prolonged postoperative ventilation, acute lung injury, and acute respiratory distress syndrome ...
Kim A. Dora, Christopher P. Stanley, Emad Al Jaaly, Francesca Fiorentino, Raimondo Ascione, Barnaby C. Reeves, Gianni D. Angelini   +6 more
doaj   +1 more source

Weight as an assay-independent predictor of poor response to enteric aspirin in cardiovascular patients

Platelets, 2020
Aspirin non-response is associated with poor outcome but there is no agreement between the different methods to asses it. Weight has been shown to be a predictor of poor response but only using one method.
Meadhbh McCall, Aaron Peace, Anthony F Tedesco, David Foley, Ronán M Conroy, Dermot Cox   +5 more
doaj   +1 more source