Results 161 to 170 of about 132,893 (224)

Degree of Cyclooxygenase-2 Inhibition Modulates Blood Pressure Response. [PDF]

Hypertension
Theken KN, Ghosh S, Skarke C, Fries S, Lahens NF, Sarantopoulou D, Grant GR, FitzGerald GA, Grosser T.   +8 more
europepmc   +1 more source

A monoclonal anti-thromboxane B2 antibody [PDF]

FEBS Letters, 1988
A monoclonal antibody against thromboxane B2 which may be used in standard fluid phase radioimmunoassays with a detection limit of around 40 pg and a binding affinity of 1.98 × 109 M−1 is described.
Margot Reinke, Brune, Kay, Reinke, Margot, Kay Brune   +3 more
exaly   +2 more sources

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A radioimmunoassay for thromboxane B2

Analytical Biochemistry, 1977
Abstract Thromboxane B 2 levels are believed to reflect the levels of the active precursor thromboxane A 2 , present during biosynthetic transformations of arachidonic acid. A radioimmunoassay for thromboxane B 2 is described. The antibodies show selective recognition of the thromboxane B structure with a sensitivity of 100 pg.
F A, Fitzpatrick, R R, Gorman, J C, Mc Guire, R C, Kelly, M A, Wynalda, F F, Sun   +5 more
openaire   +2 more sources

Enzyme immunoassay of thromboxane B2

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
An immunoassay for thromboxane B2 was developed in which the hapten molecule was labeled with beta-galactosidase. The immunoprecipitate formed after competition between enzyme-labeled and unlabeled thromboxane B2 was subjected to a fluorometric assay of beta-galactosidase. Thromboxane B2 was detectable in the range of 0.1-30 pmol.
Y, Hayashi, N, Ueda, K, Yokota, S, Kawamura, F, Ogushi, Y, Yamamoto, S, Yamamoto, K, Nakamura, K, Yamashita, H, Miyazaki, K, Kato, S, Terao   +11 more
openaire   +2 more sources

Synthesis of thromboxane B2 metabolites

Prostaglandins, 1978
This paper reports the synthesis of 11-dehydrothromboxane B2 methyl ester (II), 15-dehydrothromboxane B2 methyl ester (III), 15-dehydro-13, 14-dihydrothromboxane B2 (XII) and 2,3-dinorthromboxane B2 methyl ester (XV). These compounds, as their free acids, have been reported to be thromboxane metabolites.
N A, Nelson, R W, Jackson, O K, Sebek
openaire   +2 more sources

Development of radioimmunoassay for thromboxane B2

Analytical Biochemistry, 1978
Abstract A sensitive and specific radioimmunoassay for thromboxane B 2 has been developed. Thromboxane B 2 antiplasma was produced in rabbits by repeated immunization with thromboxane B 2 coupled to bovine serum albumin. [ 125 I]-labeled antigen with high specific activity was prepared by radioiodination of thromboxane B 2 -tyrosine methyl ester ...
H H, Tai, B, Yuan
openaire   +2 more sources

Circulating and urinary thromboxane B2 metabolites in the rabbit: 11-dehydro-thromboxane B2 as parameter of thromboxane production

Prostaglandins, 1986
The metabolism of thromboxane B2 was studied in the rabbit. The aim of the study was to identify metabolites in blood and urine that might serve as parameters for monitoring thromboxane production in vivo. [5,6,8,9,11,12,14,15-3H8]-Thromboxane B2 was administered by i.v.
P, Westlund, M, Kumlin, A, Nordenström, E, Granström   +3 more
openaire   +2 more sources

A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation

Thrombosis Research, 1980
Abstract A radioimmunoassay for measuring thromboxane B2 with thromboxane B2-125I-tyramide was developed. Antibody to thromboxane B2 that was produced in rabbits immunized with conjugates of thromboxane B2 coupled to bovine serum albumin had a high specificity to thromboxane B2 Thromboxane B2-125I-tyramide had a high affinity to antiplasma of ...
H, Koh, A, Inoue, N, Mashimo, F, Numano, H, Maezawa   +4 more
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Embryopathic effects of thromboxane B2 in the chick

Prostaglandins and Medicine, 1981
Several prostaglandins of the E and F series are now known to be involved in reproduction and developmental events. However, there is as yet no such evidence for any of the other arachidonate metabolites. Thromboxane B2 is the stable metabolic end product of the biologically active but unstable intermediate thromboxane A.
S H, Gilani, T V, Persaud
openaire   +2 more sources