Results 71 to 80 of about 132,893 (224)

Total Synthesis of Thromboxane B2 via a Key Bicyclic Enal Intermediate [PDF]

, 2020
A 12-step asymmetric synthesis of thromboxane B2 (TxB2) from 2,5-dimethoxytetrahydrofuran is described. The synthesis employs our organocatalytic aldol reaction of succinaldehyde to give a key bicyclic enal intermediate. From here, the synthetic strategy
Aggarwal, Varinder K., Jing, Changcheng
core   +1 more source

Effects of combined therapy with atorvastatin and polyunsaturated omega-3 fatty acids on lipid profile, lipoprotein-associated phospholipase A2 and thromboxane

Кардиоваскулярная терапия и профилактика, 2010
Aim. To study the effects of the combined therapy with atorvastatin and polyunsaturated omega-3 fatty acids (omega-3 PUFA) on lipid profile, lipoprotein-associated phospholipase A2 (Lp-PLA (2)), and thromboxane B2. Material and methods.
G. F. Piksina, Yu. A. Shuvalova, V. I. Kaminnaya, Yu. V. Dotsenko, V. N. Titov, V. V. Kukharchuk, A. I. Kaminny   +6 more
doaj  

Aspirin resistance and ischemic heart disease on Iranian experience

Advanced Biomedical Research, 2012
Background: Coronary artery disease (CAD) and myocardial infarction are the most common causes of mortality and morbidity all over the world.
Masoumeh Sadeghi, Afsoon Emami, Naghmeh Ziyaei, Majid Yaran, Allahyar Golabchi, Azam Sadeghi   +5 more
doaj   +1 more source

Determinants of reduced antiplatelet effect of aspirin in patients with stable coronary artery disease. [PDF]

PLoS ONE, 2015
Aspirin is a cornerstone in management of coronary artery disease (CAD). However, considerable variability in the antiplatelet effect of aspirin has been reported.To investigate independent determinants of reduced antiplatelet effect of aspirin in stable
Sanne Bøjet Larsen, Erik Lerkevang Grove, Søs Neergaard-Petersen, Morten Würtz, Anne-Mette Hvas, Steen Dalby Kristensen   +5 more
doaj   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

Bradykinin-induced release of thromboxane B2 into bronchoalveolar lavage fluid of guinea pigs: relationship to airflow obstruction

, 1995
The aim of this study was to evaluate the role of thromboxane A2 in bradykinin-induced airflow obstruction in guinea pig in vivo. Airway insufflation pressure (Pi) was measured to assess airflow obstruction and the thromboxane B2 (a stable metabolite of ...
Petersson, Maud, Löfdahl, Claes-Göran,, Arakawa, Hirokazu, Löfdahl, Claes-Göran, Ivana Kawikova, Bengt-Eric Skoogh, Skoogh, Bengt-Eric, Claes-Göran Löfdahl, Hirokazu Arakawa, Lotvall, Jan, Jan Lötvall, Kawikova, Ivana, Lund University., Maud Petersson   +13 more
core   +1 more source

B2-InF First set of PR Material

, 2021
The B2-InF consortium is now embarking in the first stages of its research and analysis. This first set of PR material is meant to introduce the purpose of this noble project to the public, leading it to stay informed about developments.
B2-InF Consortium
core   +1 more source

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy, Koyeli Girigoswami, Agnishwar Girigoswami   +2 more
wiley   +1 more source

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source

The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans [PDF]

, 1983
The effect of insoluble glucan synthesized by Streptococcus mutans on [3H]arachidonate metabolites secretion from peritoneal macrophages was studied. Insoluble glucans stimulated [3H]arachidonate release and secretion of prostaglandin E2 and thromboxane ...
Shibata, Yasuko, Yasuko Shibata, Takiguchi, Hisashi, Abiko, Yoshimitsu, Hisashi Takiguchi, Yoshimitsu Abiko, Seidai Murai, Kazuo Fukushima, Fukushima, Kazuo, Murai, Seidai   +9 more
core   +1 more source