Results 161 to 170 of about 5,098,470 (266)

Thymic Epithelial Cell Alterations and Defective Thymopoiesis Lead to Central and Peripheral Tolerance Perturbation in MHCII Deficiency. [PDF]

Front Immunol, 2021
Ferrua F, Bortolomai I, Fontana E, Di Silvestre D, Rigoni R, Marcovecchio GE, Draghici E, Brambilla F, Castiello MC, Delfanti G, Moshous D, Picard C, Taghon T, Bordon V, Schulz AS, Schuetz C, Giliani S, Soresina A, Gennery AR, Signa S, Dávila Saldaña BJ, Delmonte OM, Notarangelo LD, Roifman CM, Poliani PL, Uva P, Mauri PL, Villa A, Bosticardo M.   +28 more
europepmc   +1 more source

Chronic Rhinosinusitis and Nasal Polyps in Eosinophilic Granulomatosis With Polyangiitis: A Scoping Review

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 996-1011, September 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is one of the most common manifestations of eosinophilic granulomatosis with polyangiitis (EGPA), often preceding the diagnosis of systemic vasculitis by several years. The sinonasal presentation of EGPA typically resembles CRS with nasal polyps (CRSwNP), making it clinically indistinguishable from those
Alisha Sharma, Alyssa Y. Li, Teruko Kishibe, Dennis Wong, Kevin M. Sanders, Maggie Jiang, Heedo Lee, Christine Song, Kieran Mcintyre, Christian Pagnoux, Yvonne Chan, John M. Lee, Daniel J. Lee   +12 more
wiley   +1 more source

BM-MSC-derived migrasomes reverse stroke-induced thymic atrophy and immunosuppression via Pin1 delivery to thymic epithelial cells

Journal of Neuroinflammation
Acute ischemic stroke triggers immunosuppression, yet existing therapies struggle to balance neuroprotection with poststroke immunosuppression. We demonstrated that bone marrow mesenchymal stem cells (BM-MSC) reverse stroke-induced thymic atrophy by ...
Haotong Yi, Mengyan Hu, Liling Yuan, Xiaotao Su, Shilin Wu, Tiemei Li, Shisi Wang, Xinmei Kang, Yuxin Liu, Zhiruo Liu, Qin Qin, Weihua Yu, Yifan Li, Wei Qiu, Wei Cai, Zhengqi Lu   +15 more
doaj   +1 more source

miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation. [PDF]

J Exp Med, 2021
Dong J, Warner LM, Lin LL, Chen MC, O'Connell RM, Lu LF.   +5 more
europepmc   +1 more source

Roles of Interleukin‐31 in Allergen‐Driven Cough: Linking Protease‐Activated Receptor‐2 Activation and Vagal Ganglion Sensitization in a Dermatophagoides farinae‐Induced Asthma Model

Brain and Behavior, Volume 16, Issue 9, September 2026.
In a Dermatophagoides farinae‐induced asthma model, IL‐31 deficiency did not substantially alter airway inflammation or immune responses but prevented the allergen‐induced enhancement of PAR‐2 expression and responsiveness in vagal sensory neurons.
Takayoshi Miyamoto, Chiharu Ohira, Mao Kaneki, Mariko Komuro, Mana Ichikawa, Ibuki Yasuda, Yoshiichi Takagi, Tomoki Fukuyama   +7 more
wiley   +1 more source

Laryngeal NUT Carcinoma With BRD4::NUTM1 Fusion: A 4‐Year Clinical Course Highlighting the Limitations of Current Multimodal Therapy

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Nuclear protein in testis (NUT) carcinoma is a rare, aggressive malignancy driven by NUTM1 rearrangement, often misdiagnosed as squamous cell carcinoma, with no established standard therapy. This report describes the clinical course and treatment resistance in primary laryngeal NUT carcinoma and provides insights into potential ...
Masafumi Kanno, Chiai Sasaki, Eiichi Kato, Hoshino Terada, Nobuhiro Hanai, Eiichi Sasaki, Mana Fukushima, Toshiki Masuishi, Keisuke Takanari, Yasuto Fukada, Yuto Miyazaki, Yuki Sonoda, Yukinori Kato, Taiyo Morikawa, Tetsuji Takabayashi, Shigeharu Fujieda   +15 more
wiley   +1 more source

Neonatal Exposure to Antibiotics Triggers Obesity in Adulthood by Permanent Microbiota Dysbiosis and Reduction of Adipose Regulatory T Cells

Barrier Immunity, Volume 2, Issue 3, Page 147-164, September 2026.
ABSTRACT Neonatal dysbiosis of the gut microbiota represents a critical environmental factor promoting obesity, but the underlying immunological mechanisms remain unknown. We show here that neonatal treatment of mice with broad‐spectrum antibiotics for the first 3 weeks of life (NeoATB) resulted in the development of obesity and metabolic abnormalities
Peter Zanvit, Junji Xu, Wenjing Yang, Nancy Guo, Tianming Yu, Xue Jiao, Michaela Prochazkova, Wenwen Jin, Na Liu, Sang‐A Park, Cheryl Chia, Daxesh P. Patel, Dunfang Zhang, Nathan Goldberg, Alexander Cain, Frank J. Gonzalez, Yasmine Belkaid, Yingzi Cong, WanJun Chen   +18 more
wiley   +1 more source

Herbal Extracts and Plant‐Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Food‐derived bioactives, herbal extracts, and standardized botanical products are being investigated as adjunctive strategies for atopic dermatitis. Their biological activity is shaped not only by plant source and nominal dose, but also by fermentation, drying, heating, extraction, food‐matrix binding, gastrointestinal transformation, and formulation ...
Muhuang Zeng, Qianlan Yuan, Shuojia Huang, Xiaofei Lu   +3 more
wiley   +1 more source

Thymic Medullary Epithelial Cell [PDF]

, 2020
openaire   +1 more source

Plant Flavonoid—Enriched Functional Foods for Polycystic Ovary Syndrome: Dietary Sources, Bioavailability Enhancement, and Personalized Intervention Strategies

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Plant flavonoids from fruits, vegetables, tea, and soybeans require food processing technologies (microencapsulation, nano‐encapsulation, lipid carriers, fermentation, food collaboration) to enhance bioavailability, enabling the development of functional foods for precision dietary intervention in PCOS.
Jianding Wang, Hejian Zhu, Qing Shen, Yinghua Zhong, Yunli Du, Wenxi Yu, Fang Mao, Zhitao Yao, Weiwei Zhu, Lirong Sun, Qiu Lin, Xiaomin Xu, Jiong Zhu   +12 more
wiley   +1 more source