Results 161 to 170 of about 21,196 (261)

The last step to achieve barrier damage control

Frontiers in Immunology
Heterogeneity characterises inflammatory diseases and different phenotypes and endotypes have been identified. Both innate and adaptive immunity contribute to the immunopathological mechanism of these diseases and barrier damage plays a prominent role ...
Ilaria Baglivo, Stefania Colantuono, Arianna Lumaca, Alfredo Papa, Antonio Gasbarrini, Cristiano Caruso   +5 more
doaj   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

International Journal of Dermatology, Volume 65, Issue 2, Page 257-272, February 2026.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari, Reinaldo Falavigna Tovo, Daniela Franco Bueno   +2 more
wiley   +1 more source

Mechanistic study on the alleviation of LPS-induced hepatocyte injury by thymic stromal lymphopoietin

Guangxi Yike Daxue xuebao
Objective To explore the mechanism of thymic stromal lymphopoietin (TSLP) in regulating lipopolysaccharide (LPS) -induced inflammation in mouse hepatocytes. Methods Ten male C57BL/6J wild-type (WT) mice and 10 male TSLP receptor-deficient (TSLPR-/-) mice
Jiarui ZHANG, Shaolei WU, Shilai LI
doaj   +1 more source

Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. [PDF]

, 2019
Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics.
Broide, David H, Hur, Gyu Young
core  

Relationship between meconium staining and thymic stromal lymphopoietin.

European review for medical and pharmacological sciences, 2014
Epithelium-derived thymic stromal lymphopoietin (TSLP), is a key pro-allergic cytokine that has recently been linked to chronic airway diseases. Our aim is to determine cord blood TSLP levels in pregnancies with meconium stained amniotic fluid.A total of 44 pregnant women with meconium stained amniotic fluid and a total of 44 healthy pregnant women ...
Mollamahmutoglu, L., Engin-Ustun, Y., Ozkan, M. S., Demirtas, CANAN, Yenicesu, O., Eyi, E. G. Y., Aktulay, A.   +6 more
openaire   +2 more sources

Risk factors for inflammatory obstructive pulmonary diseases: a prospective cohort study [PDF]

, 2013
科学研究費助成事業(科学研究費補助金)研究成果報告書：基盤研究(C)2010-2012課題番号 ...
Sakamoto Tohru, 坂本 透
core  

Paradoxical eosinophilic and cytokine responses to oral corticosteroid treatment in patients with asthma exacerbations

Journal of Allergy and Clinical Immunology: Global
Background: Thymic stromal lymphopoietin (TSLP) orchestrates eosinophilic inflammation, which may increase during asthma exacerbations. In contrast, microRNA-1 (miR-1) inhibits TSLP-mediated eosinophil trafficking in lung endothelium. Whether the balance
Kittipong Maneechotesuwan, MD, PhD, Nattakarn Prapruetkit, MD, Jirabhorn Chankham, MD, Jirawat Assawabhumi, BS, Kanda Kasetsinsombat, MSc, Peter J. Barnes, FRS, FMedSci   +5 more
doaj   +1 more source

Dimeric procyanidins as modulators of airway inflammation in the context of allergic asthma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Human Physiology at Massey University, Manawatū, Palmerston North, New Zealand [PDF]

, 2017
Procyanidins are polyphenolic compounds that have come to be known as biologically active in the context of promoting human health. Epidemiological evidence suggests that populations that consume diets rich in procyanidins are less susceptible to ...
Coleman, Sara L
core  

Thymic Stromal Lymphopoietin [PDF]

, 2020
openaire   +1 more source

Mucosal vaccination with long-form TSLP induces migratory cDC1-mediated adaptive immunity against SARS-CoV-2 infection

Journal of Virology
A combination of vaccination strategies will potentially be required for effective control of the virus pandemic. We report that mice intranasally immunized with commercial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subunit vaccines ...
Jing Hu, Housheng Zheng, Wei Ran, Xuefei Wang, Chenghui Liao, Jian Zhou, Liang Ye   +6 more
doaj   +1 more source