Results 41 to 50 of about 16,647 (226)

Elevated Plasma Thymic Stromal Lymphopoietin After Acute Myocardial Infarction

Frontiers in Cardiovascular Medicine, 2022
BackgroundThymic stromal lymphopoietin (TSLP), a distant paralog of the cytokine IL-7, has been shown to be associated with atherosclerosis. However, the effect of plasma TSLP level after acute myocardial infarction (AMI) remains largely unclear.
Yuhao Zhao, Yeping Zhang, Zongsheng Guo, Zheng Ma, Ye Liu, Chunming Han, Xinchun Yang, Lei Zhao   +7 more
doaj   +1 more source

Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells [PDF]

, 2013
Allergy is an exacerbated response of the immune system against non-self-proteins called allergens and is typically characterized by biased type-2 T helper cell and deleterious IgE mediated immune responses.
Ghaemmaghami, Amir M., Salazar, Fabian
core   +1 more source

Thymic Stromal Lymphopoietin Induction Suppresses Lung Cancer Development

Cancers, 2022
Lung cancer is the leading cause of cancer deaths in the United States and across the world. Immunotherapies, which activate tumor-infiltrating cytotoxic T lymphocytes, have demonstrated efficacy for the treatment of advanced-stage lung cancer. However, the potential for harnessing the immune system against the early stages of lung carcinogenesis to ...
Ranya Guennoun, Jennet Hojanazarova, Kathryn E. Trerice, Marjan Azin, Matthew T. McGoldrick, Erik B. Schiferle, Michael P. Stover, Shadmehr Demehri   +7 more
openaire   +2 more sources

Beneficial autoimmunity at body surfaces – immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer [PDF]

, 2014
Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental ...
Agrawal, Aguado, Al-Shami, Allakhverdi, Angkasekwinai, Arwert, Balkwill, Bas, Björkström, Blais, Boyden, Briot, Bryson, Burnet, Burnet, Cella, Cerwenka, Champsaur, Chan, Chao, Chavanas, Chen, Chen, Cheroutre, Conticello, Coussens, Culig, Dalton, Dearman, Deleuran, Demehri, DePinho, Devey, Di Piazza, Dighe, Dunham, Dunn, Dvorak, Ehrlich, Eisenbarth, Ellyard, Engkilde, Eyerich, Farhadi, Felices, Fort, Fritz, Fujisawa, Fukuyama, Furmanski, Fux, Gause, Gebhardt, Giangreco, Girardi, Girardi, Girardi, Golumbek, Gregory, Groh, Gutierrez, Hallett, Hammad, Hams, Harris, Hayday, Heneghan, Hock, Hueber, Humphreys, Imai, Indra, Jackson, Jameson, Jameson, Jensen-Jarolim, Jerde, Jiang, Jiang, Josephs, Jotwani, Jovanovic, Jovanovic, Jung, Kaplan, Karagiannis, Kim, Komai-Koma, Kool, Kool, Kouzaki, Kuroda, Lebel-Binay, Lee, Lindelof, Lodoen, Ma, Magalhaes, Magalhaes, Marichal, Marichal, Matsuda, Matzinger, McCoy, McWhorter, Meehan, Metz, Mishra, Moghaddam, Monticelli, Nestle, Nigro, Obiri, Oh, Okumura, Olver, Ortiz-Urda, Owyang, Palm, Palm, Park, Pastorelli, Pearce, Pedroza-Gonzalez, Pericle, Profet, Qi, Ramsbottom, Raulet, Reali, Renard, Rittmeyer, Rodolfo, Rosenberg, Rölle, Saenz, Sagiv, Salgame, Salimi, Schmidt, Schmitz, Schneider, Schonthaler, Senovilla, Shankaran, Sharp, Sherman, Shi, Shibuya, Simson, Skinnider, Smyth, Soriani, South, Strid, Strid, Strid, Suárez-Alvarez, Swamy, Takahashi, Takai, Tan, Tang, Thomas, Traidl-Hoffmann, Turchinovich, Ullrich, Van Belle, Van Hemelrijck, Vantourout, Verdino, Vernersson, Vesely, Villarreal, Walley, Walter, Wang, Wen, Wen, Wilson, Witherden, Witherden, Wood, Yanaba, Yin, Yoo, Zaiss, Zaph, Zaph, Ziegler, Zitvogel   +190 more
core   +9 more sources

Virtual screening for inhibitors of the human TSLP:TSLPR interaction [PDF]

, 2017
The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) plays a pivotal role in the pathophysiology of various allergy disorders that are mediated by type 2 helper T cell (Th2) responses, such as asthma and atopic dermatitis.
AA Bogan, AC Braisted, AJ Souers, C Ghirelli, D Sun, DR Hall, G Neudert, G Pérez-Hernández, GM Gauvreau, HH Loeffler, J Corren, J Felix, J Yin, JM Wang, K Lindorff-Larsen, K Verstraete, K Verstraete, L Deng, LS Park, M Guillot-Delost, M Noti, M Piazza Di, MJ Abraham, NS Redhu, O Trott, P Buchwald, P Chames, RL Rich, S Demehri, S Doerr, S Ulrich, SD Levin, SF Ziegler, T Clackson   +33 more
core   +2 more sources

Sebaceous gland rich skin is characterized by TSLP expression and distinct immune surveillance which is disturbed in rosacea [PDF]

, 2017
K
Bácsi, Attila, Béke, Gabriella, Bíró, Tamás, Dajnoki, Zsolt, Gáspár, Krisztián, Hendrik, Zoltán, Juhász, István, Kapitány, Anikó, Mócsai, Gábor, Rühl, Ralph, Szegedi, Andrea, Töröcsik, Dániel, Zouboulis, Christos C.   +12 more
core   +1 more source

Thymic stromal lymphopoietin: a new cytokine in asthma [PDF]

Current Opinion in Pharmacology, 2008
Airway epithelial cells provide mechanical and immune protection against pathogens and allergens. Following activation, these cells produce a wide range of cytokines including thymic stromal lymphopoietin (TSLP). Recently it was established that a high level of TSLP is associated with asthma in mice and in humans.
Yrina, Rochman, Warren J, Leonard
openaire   +2 more sources

Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease [PDF]

, 2015
OBJECTIVE: The short isoform of thymic stromal lymphopoietin (TSLP), a cytokine constitutively expressed by epithelial cells, is crucial in preserving immune tolerance in the gut.
Alastair Forbes, Alessandra Pasini, Alessandro Vanoli, Andoh, Antonio Di Sabatino, Biancheri, Bjerkan, Caruso, Christmann, Ciccocioppo, Ciccocioppo, Cinzia Papadia, Comeau, Corazza, Cristina Ubezio, Datta, Daum, Di Sabatino, Di Sabatino, Di Sabatino, Di Sabatino, Eleanor Wood, Fornasa, Gino R Corazza, Giulia Fornasa, He, Iliev, Iliev, Iliev, Kashyap, Katerina Tsilingiri, Liu, Maria Rescigno, Monteleone, Monteleone, Nagarkar, Otte, Paolo Biancheri, Paolo Giuffrida, Pender, Pender, Rescigno, Rimoldi, Roan, Rubio-Tapia, Spadoni, Sylvia L F Pender, Takai, Thomas, Thomas T MacDonald, Usategui, Vaira, Zhou, Ziegler   +53 more
core   +1 more source

Thymic stromal lymphopoietin does not activate human basophils [PDF]

Journal of Allergy and Clinical Immunology, 2018
International ...
Salabert-Le Guen, Nina, Hemont, Caroline, Delbove, Agathe, Poli, Caroline, Braudeau, Cécile, Fantou, Aurelie, Amouriaux, Karine, Bériou, Gaëlle, Martin, Jerome C, Colas, Luc, Soumelis, Vassili, Josien, Regis   +11 more
openaire   +4 more sources

TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway [PDF]

, 2010
Background Even though thymic stromal lymphopoietin (TSLP) has been implicated in the development of allergic inflammation, its influence on immune tolerance mediated by regulatory T cells (Treg) have not been explored.
Khoa D Nguyen, Christopher Vanichsarn, Kari C Nadeau   +2 more
core   +2 more sources