Results 41 to 50 of about 21,196 (261)

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]

, 2017
BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz, Andras Schaffer, Arturo P. Saavedra, Cipolat, Fenske, Hengameh Mirzaalian, Jean-Pierre Eliane, Lynn A. Cornelius, Mary Tabacchi, Michael Wallendorf, Raphael Kopan, Salasche, Sara Moradi Tuchayi, Seckin, Shadmehr Demehri, Sindhu Manivasagam, Stockfleth, Trevor J. Cunningham, Warino   +18 more
core   +2 more sources

Human Lung-Resident Macrophages Express and Are Targets of Thymic Stromal Lymphopoietin in the Tumor Microenvironment

Cells, 2021
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine highly expressed by epithelial cells and several innate and adaptive immune cells. TSLP exerts its biological effects by binding to a heterodimeric complex composed of TSLP receptor (TSLPR ...
Mariantonia Braile, A. Fiorelli, D. Sorriento, R. D. Di Crescenzo, M. Galdiero, G. Marone, M. Santini, G. Varricchi, S. Loffredo   +8 more
semanticscholar   +1 more source

Down-regulation of thymic stromal lymphopoietin by curcumin [PDF]

Pharmacological Reports, 2013
Thymic stromal lymphopoietin (TSLP) is a cytokine implicated in the pathogenesis of allergic diseases such as asthma, atopic dermatitis and allergic rhinitis. Curcumin has various effects such as antidepressant, antioxidant, antihyperglycemic, antitumor and anti-inflammatory.
Phil-Dong, Moon, Hyun-Ja, Jeong, Hyung-Min, Kim   +2 more
openaire   +2 more sources

TSLP signaling pathway map: a platform for analysis of TSLP-mediated signaling [PDF]

, 2014
Thymic stromal lymphopoietin (TSLP) is a four-helix bundle cytokine that plays a critical role in the regulation of immune responses and in the differentiation of hematopoietic cells. TSLP signals through a heterodimeric receptor complex consisting of an
Huang, Tai-Chung, Palapetta, Shyam Mohan, Pandey, Akhilesh, Prasad, T. S. Keshava, Raju, Rajesh, Sharma, Jyoti, Tyner, Jeffrey W., van Bodegom, Diederik, Weinstock, David M., Yoda, Akinori, Zhong, Jun, Ziegler, Steven F.   +11 more
core   +1 more source

Cryoglobulinemic Glomerulonephritis in Thymic Stromal Lymphopoietin Transgenic Mice [PDF]

The American Journal of Pathology, 2001
Mixed cryoglobulins are complexes of immunoglobulins that reversibly precipitate in the cold and lead to a systemic disease in humans. Renal involvement usually manifests as a membranoproliferative glomerulonephritis with marked monocyte infiltration and, at times, intracapillary thrombi.
S, Taneda, S, Segerer, K L, Hudkins, Y, Cui, M, Wen, M, Segerer, M H, Wener, C G, Khairallah, A G, Farr, C E, Alpers   +9 more
openaire   +2 more sources

A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis

Haematologica, 2016
Thymic stromal lymphopoietin (TSLP) stimulates in vitro proliferation of human fetal B-cell precursors. However, its in vivo role during normal human B lymphopoiesis is unknown.
Olivia L. Francis, Terry-Ann M. Milford, Shannalee R. Martinez, Ineavely Baez, Jacqueline S. Coats, Karina Mayagoitia, Katherine R. Concepcion, Elizabeth Ginelli, Cornelia Beldiman, Abigail Benitez, Abby J. Weldon, Keshav Arogyaswamy, Parveen Shiraz, Ross Fisher, Christopher L. Morris, Xiao-Bing Zhang, Valeri Filippov, Ben Van Handel, Zheng Ge, Chunhua Song, Sinisa Dovat, Ruijun Jeanna Su, Kimberly J. Payne   +22 more
doaj   +1 more source

Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]

, 2017
The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core   +2 more sources

Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis

Acta Dermato-Venereologica, 2019
Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong, Xia Wu, Wei Zhang, Jie Zhang, Xiaofan Chen, Shihong Chen, Haiyan Huang, Yong Yang, Bo Yu, Xia Dou   +9 more
doaj   +1 more source

Thymic Stromal Lymphopoietin Induces Migration in Human Airway Smooth Muscle Cells [PDF]

, 2014
Airway remodeling due to increased airway smooth muscle (ASM) mass, likely due to enhanced migration and proliferation, has been shown to be highly associated with decline in lung function in asthma.
Gounni, Abdelilah S., Movassagh, Hesam, Redhu, Naresh Singh, Shan, Lianyu   +3 more
core   +1 more source

TSLP expression in the skin is mediated via RAR-RXR pathways [PDF]

, 2018
K
de Lera, Ángel R., Gericke, Janine, Lucas, Renata, Mihály, Johanna, Rühl, Ralph, Töröcsik, Dániel, Álvarez, Susana   +6 more
core   +1 more source