The effects of various lipoxygenase metabolites of arachidonic acid (AA) were investigated on the growth of freshly isolated human bone marrow mononuclear cells and marrow stromal cell cultures. LTB4, LXA4, LXB4, 12-HETE and 15-HETE (1 μM) decreased [3H]-
V. Desplat +5 more
doaj +1 more source
T cell growth factor: parameters of production and a quantitative microassay for activity.
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the ...
S. Gillis +3 more
semanticscholar +1 more source
Human Keratinocytes Catabolize Thymidine
Human neonatal foreskin keratinocytes incorporate exogenous thymidine into DNA and proliferate in vitro even after reaching confluence. Keratinocytes also catabolize thymidine, as reported for the first time below. Stratified cultures of keratinocytes reduced the amount of thymidine in the medium by more than 90% within 2 to 4 h. Consequently, the rate
Schwartz, Pauline M. +4 more
openaire +2 more sources
Thymidine phosphorylase (TP) is a rate-limiting enzyme in the thymidine catabolic pathway. TP is identical to platelet-derived endothelial cell growth factor and contributes to tumour angiogenesis.
Sho Tabata +21 more
doaj +1 more source
Early prediction of pathologic response to neoadjuvant treatment of breast cancer: use of a cell-loss metric based on serum thymidine kinase 1 and tumour volume [PDF]
Bernhard Tribukait
openalex +1 more source
Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
A Ewing +12 more
core +2 more sources
Studies on the cornin extracted from bovine liver. II. Inhibitory effect of the cornin on DNA synthesis and cell growth of L cells cultured in suspension [PDF]
Gornin was extracted from bovine liver. The effects of cornin on DNA synthesis were compared with its effects on cell growth using L cells growing in suspension.
Ohtsuki, Hisashi
core +1 more source
Labeling DNA with Stable Isotopes: Economical and Practical Considerations
Labeling DNA with stable isotopes to measure cell proliferation can be a technique as effective as 3H-thymidine labeling without the limitations imposed by using radioisotopes.
G.E. Black +4 more
doaj +1 more source
Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: Implications for gene therapeutic approaches [PDF]
R Thust +5 more
openalex +1 more source
Transplantation stimulates interstitial cell migration in hydra [PDF]
Migration of interstitial cells and nerve cell precursors was analyzed in Hydra magnipapillata and Hydra vulgaris (formerly Hydra attenuata). Axial grafts were made between [3H]thymidine-labeled donor and unlabeled host tissue. Migration of labeled cells
Bosch +10 more
core +1 more source

