Results 101 to 110 of about 199,261 (304)

Embryogenesis in Myrmicine Ants Combines Features of Short Germ‐Band Development With a Progressive Mode of Segmentation

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Different insect species exhibit remarkable diversity in the developmental trajectories from fertilized eggs to hatching larvae. For three myrmicine ant species, we observe a novel combination of a developmental features: small embryonic primordia, a mode of embryogenesis termed short/intermediate germ‐band development, and progressive establishment of
Chi‐Chun Fang   +5 more
wiley   +1 more source

Climate change–induced terrestrial matter runoff may decrease food web production in coastal ecosystems

open access: yesLimnology and Oceanography, EarlyView.
Abstract Climate change is projected to cause elevated precipitation in northern Europe, leading to increased runoff of terrestrial matter to coastal areas. The consequences for food web production and ecosystem function remain unclear. A mesocosm experiment was performed to investigate the impacts of elevated terrestrial matter input, using a natural ...
Owen F. Rowe   +12 more
wiley   +1 more source

A Method for the Isolation of 2-Deoxy-D-ribose from Thymidine. [PDF]

open access: bronze, 1956
S. Laland   +4 more
openalex   +1 more source

Combining Laser‐Induced Edition to Collision‐Induced Sequencing of Digital Oligomers in a Single Gas‐Phase Experiment

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale To increase the confidentiality level of molecular tags, binary information can be hidden in sequence‐defined oligomers using isobaric monomers including a photo‐sensitive one, which mass can be modified upon light irradiation. Reading such secured data requires light edition prior to MS/MS sequencing, which was investigated here in ...
Clothilde Comby‐Zerbino   +3 more
wiley   +1 more source

Dimeric DNA Aptamers for the Spike Protein of SARS‐CoV‐2 Derived from a Structured Library with Dual Random Domains

open access: yesSmall Methods, EarlyView.
Dimeric in a single go: A novel DNA aptamer library has been designed to yield dimeric aptamers in a single in vitro selection. Tested against the SARS‐CoV‐2 spike protein, this dual random domain (DRD) library with two 25‐nucleotide random regions and a 20‐nucleotide poly‐thymidine linker produced high‐affinity dimeric aptamers with KD values as low ...
Ryan Amini   +6 more
wiley   +1 more source

Disease Aggravation With Age in an Experimental Model of Multiple Sclerosis: Role of Immunosenescence

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Age‐related differences in EAE outcomes stem from combined peripheral and CNS factors. Key peripheral adaptive immunity changes include altered naïve/memory T cell ratios, Th1 skewing, increased suppressive Tregs, CD4+ T cell exhaustion, enhanced B cell antigen presentation, and reduced NK cell cytotoxicity.
María Dema   +6 more
wiley   +1 more source

Elimination of 15N-thymidine after oral administration in human infants.

open access: yesPLoS ONE
BackgroundWe have developed a new clinical research approach for the quantification of cellular proliferation in human infants to address unanswered questions about tissue renewal and regeneration.
Niyatie Ammanamanchi   +21 more
doaj   +1 more source

Large‐Scale Clustered Transcriptional Silencing Associated With Cellular Senescence

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Senescence inducing stimuli leads to large‐cluster hypercondensed DNA globules. This architectural phenomenon is associated with geographically clustered transcriptional repression. Such large‐scale clustered silencing of chromosomal segments may drive deep senescence through two possible ways: (1) one or more critical combination of genes, for example
Aditi U. Gurkar   +4 more
wiley   +1 more source

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

open access: yesAging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik   +20 more
wiley   +1 more source

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