Results 11 to 20 of about 312,982 (289)
Science and Technology of Advanced Materials, 2008 The magnetic field effect (MFE) in conjunction with laser flash photolysis has been used for the study of the interaction of one of the small drug like quinone molecules, 2-methyl, 1,4-naphthoquinone, commonly known as menadione (MQ), with one of the DNA
Adity Bose, Debarati Dey and Samita Basu
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Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. [PDF]
, 2020 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disorder caused by mutations in TYMP, leading to a deficiency in thymidine phosphorylase and a subsequent systemic accumulation of thymidine and 2'-deoxyuridine.
Antunes, NJ +8 more
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Pharmaceutical Sciences and Research, 2020 The accurate measurement of thymidine absorbance in the presence of sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in ethanol and water systems at room temperature by UV-vis technique has been reported.
Indu M. Paudel, Ajaya Bhattarai
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Genes and Environment, 2022 Introduction α-Tocopherol phosphate, a natural water-soluble α-tocopherol analog, exists in biological tissues and fluids. Synthesized α-tocopherol phosphate is used as an ingredient of cosmetics.
Toshinori Suzuki, Chiaki Ono
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Pathways of thymidine hypermodification [PDF]
Nucleic Acids Research, 2021 Abstract The DNAs of bacterial viruses are known to contain diverse, chemically complex modifications to thymidine that protect them from the endonuclease-based defenses of their cellular hosts, but whose biosynthetic origins are enigmatic.
Yan-Jiun Lee +19 more
openaire +2 more sources
UVA Assisted 4-Thiothymidine for Cancer Treatment [PDF]
, 2016 This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized.
Feng, Luo +3 more
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Deoxynucleoside Therapy for Thymidine Kinase 2–Deficient Myopathy
Annals of Neurology, 2019 Thymidine kinase 2, encoded by the nuclear gene TK2, is required for mitochondrial DNA maintenance. Autosomal recessive TK2 mutations cause depletion and multiple deletions of mtDNA that manifest predominantly as a myopathy usually beginning in childhood
C. Domínguez-González +26 more
semanticscholar +1 more source
Dexamethasone pretreatment impairs the thymidylate synthase inhibition mediated flare in thymidine salvage pathway activity in non-small cell lung cancer. [PDF]
PLoS ONE, 2018 INTRODUCTION:Successful inhibition of thymidylate synthase (TS) by pemetrexed, a TS inhibitor, results in a reproducible transient burst or "flare" in thymidine salvage pathway activity at 2 hrs.
Xiao Chen, Yizeng Yang, Sharyn I Katz
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Gastroprotective effects of oral nucleotide administration [PDF]
, 2006 BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A +4 more
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A critical examination of substoichiometric isotope dilution analysis using thymidine and leucine
Scientia Marina, 1999 Isotope dilution analysis is used to determine the specific activity of radiolabelled precursors such as 3H-thymidine and 3H-leucine incorporated into DNA or protein in environmental samples.
David F. Bird
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