Results 21 to 30 of about 127,095 (220)
EFFECTS OF INTESTINALLY ABSORBED THYMIDINE ON TRITIATED THYMIDINE UTILIZATION
Cell Proliferation, 1979 ABSTRACTExperimental evidence presented suggests that [3H]TdR can be rapidly and efficiently transported from the intestine to the systemic circulation. This pathway for thymidine transport may be physiologically important since administration of cold thymidine in the drinking water enhances the utilization of a parenterally injected dose of [3H]TdR in
R P, Williams, I L, Cameron, E K, Adrian
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Hydrogen Peroxide-Induced Thymidine Incorporation Into Cultured Rat Astrocytes
Journal of Pharmacological Sciences, 2006 We characterized [methyl-3H]thymidine ([3H]thymidine) and [5-3H]uridine ([3H]uridine) incorporation into cultured astrocytes and neurons in the presence and absence of hydrogen peroxide (H2O2) in order to define the response to oxidative stress in the ...
Koh-ichi Tanaka +3 more
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Molecular Therapy: Methods & Clinical Development, 2018 Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metabolic ...
Michelle Levene +5 more
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Acta Societatis Botanicorum Poloniae, 2015 Hydroxyurea treatment of onion roots induced mitotic block which was released by transfer of bulbs to water, and also to some extent by addition of cold or 3H-thymidine to hydroxyurea solutions.
H. Habdas
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Inhibitory Effect of Bridged Nucleosides on Thermus aquaticus DNA Polymerase and Insight into the Binding Interactions. [PDF]
PLoS ONE, 2016 Modified nucleosides have the potential to inhibit DNA polymerases for the treatment of viral infections and cancer. With the hope of developing potent drug candidates by the modification of the 2',4'-position of the ribose with the inclusion of a bridge,
Sung-Kun Kim +5 more
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Frontiers in Pediatrics, 2022 BackgroundPatients with T cell deficiency <10% of normal proliferation are indicated to receive immune reconstruction by hematopoietic stem cell transplantation (HSCT).
Hsin-Ju Lee +13 more
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PLoS ONE, 2020 Bacterial production has been often estimated from DNA synthesis rates by using tritium-labeled thymidine. Some bacteria species cannot incorporate extracellular thymidine into their DNA, suggesting their biomass production might be overlooked when using
Kenji Tsuchiya +8 more
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Frontiers in PharmacologyIntroductionTo evaluate the anti-cardiomyopathic activity of thymine (Thy) and to elucidate its mechanism of action.MethodsTransgenic zebrafish with enhanced green fluorescent protein (EGFP)-labelled hearts (Tg (cmlc2: EGFP)) and wild-type AB zebrafish ...
Bin Li +13 more
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Assessment of Thymidine Phosphorylase Function: Measurement of Plasma Thymidine (and Deoxyuridine) and Thymidine Phosphorylase Activity [PDF]
, 2011 We describe detailed methods to measure thymidine (dThd) and deoxyuridine (dUrd) concentrations and thymidine phosphorylase (TP) activity in biological samples. These protocols allow the detection of TP dysfunction in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Martí R, López LC, Hirano M.
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Frontiers in Cellular and Infection Microbiology, 2017 Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate synthase gene thyA, which can ...
Irene Rodríguez-Arce +20 more
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