Results 81 to 90 of about 199,261 (304)
Hydrogen Peroxide-Induced Thymidine Incorporation Into Cultured Rat Astrocytes
Journal of Pharmacological Sciences, 2006 We characterized [methyl-3H]thymidine ([3H]thymidine) and [5-3H]uridine ([3H]uridine) incorporation into cultured astrocytes and neurons in the presence and absence of hydrogen peroxide (H2O2) in order to define the response to oxidative stress in the ...
Koh-ichi Tanaka +3 more
doaj
Thymidine phosphorylase is angiogenic and promotes tumor growth.
Proceedings of the National Academy of Sciences of the United States of America, 1995 Platelet-derived endothelial cell growth factor was previously identified as the sole angiogenic activity present in platelets; it is now known to be thymidine phosphorylase (TP).
A. Moghaddam +9 more
semanticscholar +1 more source
Chemistry – A European Journal, EarlyView.Time‐resolved nuclear magnetic resonance (NMR) and circular dichroism (CD) spectroscopy were utilized to investigate the complex G‐quadruplex folding landscape of the human telomeric DNA in the presence of the ligand Phen‐DC3. Our findings revealed significant differences in the kinetics of the pathways originating from the unfolded or K+‐bound state ...
Ines Burkhart +3 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2018 Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metabolic ...
Michelle Levene +5 more
doaj
Mediators of Inflammation, 1998 The effects of various lipoxygenase metabolites of arachidonic acid (AA) were investigated on the growth of freshly isolated human bone marrow mononuclear cells and marrow stromal cell cultures. LTB4, LXA4, LXB4, 12-HETE and 15-HETE (1 μM) decreased [3H]-
V. Desplat +5 more
doaj +1 more source
Journal of the National Cancer Institute, 1996 BACKGROUND Platelet-derived endothelial cell growth factor (PD-ECGF) is known to promote the development of new blood vessels, which are fundamental to tumor growth and metastasis.
Y. Takebayashi +8 more
semanticscholar +1 more source
Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy
ChemPlusChem, EarlyView.Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber +3 more
wiley +1 more source
ELECTROPHORESIS, EarlyView.ABSTRACT A capillary electrophoresis system capable of measuring streaming potentials was used for the determination of critical micelle concentration (CMC) of anionic, cationic, zwitterionic and non‐ionic surfactants. The CMC values of anionic surfactant sodium dodecyl sulphate (SDS), cationic surfactant cetyltrimethylammonium bromide (CTAB ...
Yuri Chenyakin, David Da Yong Chen
wiley +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source
Molecular Genetics and Metabolism Reports, 2022 We describe the case of a Greek female patient with the Classic form of the ultra- rare and fatal autosomal recessive disorder Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) and the impact of allogeneic hematopoietic stem cell ...
A. Paisiou +16 more
doaj