Results 71 to 80 of about 5,593 (118)

Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab. [PDF]

Sci Rep
Shibutani M, Tanda H, Kasashima H, Fukuoka T, Kashiwagi S, Maeda K.   +5 more
europepmc   +1 more source

Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans. [PDF]

Cardiovasc Ther
Hong L, Yue H, Cai D, DeHart A, Toloza-Alvarez G, Du L, Zhou X, Fan X, Huang H, Chen S, Rahaman SO, Zhuang J, Li W.   +12 more
europepmc   +1 more source

Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE. [PDF]

J Transl Med
Du J, Liu F, Liu X, Zhao D, Wang D, Sun H, Yan C, Zhao Y.   +7 more
europepmc   +1 more source

Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE. [PDF]

Mol Ther Methods Clin Dev, 2020
Meinders M, Shoemark D, Dobbe JGG, Streekstra GJ, Frayne J, Toye AM.   +5 more
europepmc   +1 more source

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: In vitro, kinetic, and in silico studies. [PDF]

PLoS One, 2020
Javaid S, Saad SM, Zafar H, Malik R, Khan KM, Choudhary MI, Rahman AU.   +6 more
europepmc   +1 more source

Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. [PDF]

J Clin Med, 2020
Kipper K, Hecht M, Antunes NJ, Fairbanks LD, Levene M, Kalkan Uçar S, Schaefer A, Blakely EL, Bax BE.   +8 more
europepmc   +1 more source

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy. [PDF]

J Clin Med, 2019
Levene M, Bain MD, Moran NF, Nirmalananthan N, Poulton J, Scarpelli M, Filosto M, Mandel H, MacKinnon AD, Fairbanks L, Pacitti D, Bax BE.   +11 more
europepmc   +1 more source

Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study. [PDF]

Molecules, 2019
Almandil NB, Taha M, Farooq RK, Alhibshi A, Ibrahim M, Anouar EH, Gollapalli M, Rahim F, Nawaz M, Shah SAA, Ahmed QU, Zakaria ZA.   +11 more
europepmc   +1 more source

Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study. [PDF]

Sci Rep, 2019
Zaman K, Rahim F, Taha M, Wadood A, Shah SAA, Ahmed QU, Zakaria ZA.   +6 more
europepmc   +1 more source

Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies. [PDF]

PLoS One, 2019
Javaid S, Shaikh M, Fatima N, Choudhary MI.   +3 more
europepmc   +1 more source