Results 121 to 130 of about 74,896 (329)

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

New alternatives in photoprotection: Preparation and evaluation of lamellar silicate derivatives and their use as sunscreens

International Journal of Cosmetic Science, EarlyView.
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila, Alice Simon, Letícia Coli Louvisse de Abreu, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Marcelo de Pádula, Lucio Mendes Cabral   +6 more
wiley   +1 more source

New insights into the putative XX/XY sex chromosomal system in blue‐eyed red‐fin pleco Hypostomus soniae (Siluriformes, Loricariidae)

Journal of Fish Biology, EarlyView.
Abstract Blue‐eyed red‐fin pleco Hypostomus soniae (family Loricariidae) presented a putative sex system XX/XY in early stage. Aiming to explore the inter‐populational karyotypic variation and proposed emergence of the XX/XY system, we studied 13 H. soniae individuals (6 males, 7 females) from the Tapajós River.
Luan Aércio Melo Maciel, Renata Coelho Rodrigues Noronha, Bruno Rafael Ribeiro de Almeida, Manoella Gemaque Cavalcante, Cleusa Yoshiko Nagamachi, Julio Cesar Pieczarka, Luís Reginaldo R. Rodrigues   +6 more
wiley   +1 more source

Characterizing the enzyme-product complexes of thymine DNA glycosylase using crystallography and NMR

, 2015
Shuja Shafi Malik, Kristen M. Varney, Edwin Pozharski, Alexander C. Drohat   +3 more
openalex   +2 more sources

Near‐complete genome assembly of a transformation‐efficient elite inbred line LH244 and its comparison with B73

Journal of Integrative Plant Biology, EarlyView.
Analysis of a near‐complete assembly of the genome of the highly transformable maize inbred line LH244 revealed its high genetic similarity to B73 and will serve as a much‐needed resource for functional genomics and genome editing of maize. ABSTRACT The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and ...
Kaiwen Tan, Xinxiang Liu, Zijian Wang, Zhengquan Zhang, Wei Huang, Shengnan Liu, Zhen Lin, Haiming Zhao, Hainan Zhao, Yang Liu, Fangpu Han, Jinsheng Lai, Weibin Song, Jiuran Zhao, Jian Chen   +14 more
wiley   +1 more source

Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair‐dependent and independent mechanisms [PDF]

, 2017
Tomohumi Nakamura, Kouichi Murakami, Haruto Tada, Yoshihiko Uehara, Jumpei Nogami, Kazumitsu Maehara, Yasuyuki Ohkawa, Hisato Saitoh, Hideo Nishitani, Tetsuya Ono, Ryotaro Nishi, Masayuki Yokoi, Wataru Sakai, Kaoru Sugasawa   +13 more
openalex   +1 more source

The environmentally responsive plant epigenome: insights from jasmonate signaling

New Phytologist, EarlyView.
Summary The environmental responsiveness of the plant epigenome is essential for spatiotemporally precise gene regulation, enabling plants to adapt to external cues. Elucidating the mechanisms underlying this responsiveness is therefore fundamental to deciphering the molecular logic of plant‐environment interactions.
Mark Zander, Emily Vesper
wiley   +1 more source

Computational Study of Thymine Dimer Radical Anion Splitting in the Self-Repair Process of Duplex DNA

, 2008
F. Masson, Teodoro Laino, Ivano Tavernelli, Ursula Röthlisberger, Jürg Hutter   +4 more
openalex   +2 more sources

Synthesis of atrans-synthymine dimer building block. Solid phase synthesis of CGTAT[t,s]TATGC [PDF]

, 1988
John‐Stephen Taylor, Ian R. Brockie
openalex   +1 more source

Identification of a Susceptibility Gene for Xanthomonas oryzae pv. oryzae in Vietnamese Elite Rice (Oryza sativa L.) Cultivar Bacthom 7

Plant Breeding, EarlyView.
ABSTRACT Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial leaf blight (BLB) disease in rice, exerting a detrimental impact on the yield of various rice cultivars in Vietnam, notably the Bacthom 7 (BT7) variety. Xoo possesses transcription activator‐like effectors (TALEs) which modulate the expression of host genes by specifically ...
Nguyen Duy Phuong, Dong Huy Gioi, Cao Le Quyen, Nguyen Xuan Hung, Ha Hai Yen, Bui Thi Thu Huong, Sebastien Cunnac, Tran Dang Xuan, Pham Xuan Hoi   +8 more
wiley   +1 more source