Results 131 to 140 of about 65,072 (224)

Spectroscopic Characteristics of Thymine Dimers

open access: yes, 2019
Cyclobutane pyrimidine dimers (CPDs’), a photoreactive product formed from the exposure of DNA to UV light, are a precursor that if not repaired by the bodies CPD-photolyases can ultimately lead to cell death or skin cancer.
Rego, Samantha
core   +1 more source

Immunological studies of thymine dimer quantitation. [PDF]

open access: yes, 1992
Thesis (M.Sc.)-University of Natal, Durban, 1992.Ultraviolet irradiation of DNA induces the formation of a number of mutagenic lesions. The most prolific of these is the cis-syn thymine dimer (formed maximally at 260 nm) and this has been implicated ...
Kriste, Angela Gayle.
core   +1 more source

Thymine-metal ion interactions: Relevance for thymine quartet structures

open access: yes, 2001
Apart from their function as counter ions for the charge neutralization of nucleic acids, alkali metal ions play important roles in stabilizing particular multistranded nucleic acids, e.g.
Lippert, Bernhard   +2 more
core   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam   +4 more
wiley   +1 more source

Alquilação seletiva na posição N1 de timina e uracil em sistema de Mitsunobu/Selective alkylation at the N1 position of thymine and uracil in the Mitsunobu system

open access: yesOrbital: The Electronic Journal of Chemistry, 2010
Selectivity of alkylation at the N1 position in pyrimidines (thymine and uracil) was achieved by the application of N3-benzoyl thymine and N3-benzoyl uracil as substrates, where the N3 atom was temporarily protected, exposing the N1 atom as the ...
Fábio D. P. Soares   +3 more
doaj  

Plant cis‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
wiley   +1 more source

The complete mitochondrial genome of Sarcophaga angarosinica (Diptera: Sarcophagidae)

open access: yesMitochondrial DNA. Part B. Resources
Sarcophaga (Liosarcophaga) angarosinica (Rohdendorf, 1937) (Diptera: Sarcophagidae) is a species of both medical and ecological significance. In this study, the complete mitochondrial genome (mitogenome) of S. angarosinica was sequenced and characterized.
Ziqi Zhou   +8 more
doaj   +1 more source

Quantitative Pharmacodynamic Analysis of Trimethoprim‐Sulfonamide Combination Activity Against Staphylococcus pseudintermedius

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead   +7 more
wiley   +1 more source

Strand breaks in deoxyribonucleic acid of thymine-starved bacteria

open access: yes, 1973
Thymine starvation of E. coli B/r resulted in a decrease in single-strand molecular weight of DNA, as determined by sedimentation in alkaline sucrose gradient.
Das, Jyotirmoy   +1 more
core   +1 more source

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