Results 21 to 30 of about 124,338 (379)
Thymine-Modified Nanocarrier for Doxorubicin Delivery in Glioblastoma Cells
Molecules, 2023 Brain tumor glioblastoma is one of the worst types of cancer. The blood–brain barrier prevents drugs from reaching brain cells and shields glioblastoma from treatment.
Albina Y. Ziganshina +10 more
doaj +1 more source
Meteorites and the RNA World: Synthesis of Nucleobases in Carbonaceous Planetesimals and the Role of Initial Volatile Content [PDF]
The Astrophysical Journal, 2023, 942, 50, 2021 Prebiotic molecules, fundamental building blocks for the origin of life, have been found in carbonaceous chondrites. The exogenous delivery of these organic molecules onto the Hadean Earth could have sparked the polymerization of the first RNA molecules in Darwinian ponds during wet-dry cycles.
arxiv +1 more source
Mapping Electronic Decoherence Pathways in Molecules [PDF]
PNAS. 120, e2309987120 (2023), 2023 Establishing the fundamental chemical principles that govern molecular electronic quantum decoherence has remained an outstanding challenge. Fundamental questions such as how solvent and intramolecular vibrations or chemical functionalization contribute to the decoherence remain unanswered and are beyond the reach of state-of-the-art theoretical and ...
arxiv +1 more source
Adenine and Thymine Effect on Quartz Dissolution at Different Artificial Seawaters
Orbital: The Electronic Journal of Chemistry, 2018 According to Bernal (1951) minerals may have played important roles in the origin of life such as: protect biomolecules against degradation by UV radiation or hydrolysis, pre-concentrate biomolecules from prebiotic seas and formation of polymers.
Dimas Augusto Morozin Zaia +2 more
doaj +3 more sources
Molecules, 2016 The present study provides new insights into the topography of the potential energy hypersurfaces (PEHs) of the thymine nucleobase in order to rationalize its main ultrafast photochemical decay paths by employing two methodologies based on the complete ...
Javier Segarra-Martí +3 more
doaj +1 more source
Synthesis of new dipeptides based on uracil and thymine and investigation of the molecular docking of these compounds as inhibitors of quorum sensing system in Pseudomonas aeruginosa [PDF]
شیمی کاربردی روز, 2019 In this study, due to the importance of dipeptide compounds in diagnosis of disease or as drug compounds, new dipeptide compounds were synthesized using pyrimidine derivatives of thymine and uracil.
Azam Heidari +3 more
doaj +1 more source
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide.
Science, 1991 A polyamide nucleic acid (PNA) was designed by detaching the deoxyribose phosphate backbone of DNA in a computer model and replacing it with an achiral polyamide backbone.
P. Nielsen +3 more
semanticscholar +1 more source
Nanomaterials, 2017 Mercury ion (Hg2+) is recognized as one of the most toxic metal ions for the environment and for human health. Techniques utilized in the detection of Hg2+ are an important factor.
Hao Yang +8 more
doaj +1 more source
Molecules, 2019 The clinically widely-used anticancer drug, cisplatin, binds strongly to DNA as a DNA-damaging agent. Herein, we investigated the interaction of cisplatin with a 15-mer single-stranded C,T-rich oligodeoxynucleotide, 5′-CCTT4CTT7G8C9T10TCTCC-3′
Wenjuan Zeng +9 more
doaj +1 more source
Surface-enhanced Raman spectroscopy of DNA bases [PDF]
, 1986 A Raman microprobe has been used to measure the surface-enhanced Raman spectra of adenine, guanine, cytosine and thymine. Comparison of the SERS spectrum with solution spectra shows that some line positions are not influenced by the adsorption process ...
Greve, J. +3 more
core +3 more sources