Results 161 to 170 of about 32,913 (197)

Reconstitution of thymopoiesis via implantation of cryopreserved cultured thymus tissue into athymic recipients. [PDF]

Am J Transplant
Hale LP, Bowles DE, Li J, Macintyre AN, Bolden N, Kurtzberg J, Medina CK, Aykut B, Tracy ET, Turek JW.   +9 more
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Single-cell multiomics identifies Tcf1 and Lef1 as key initiators of early thymic progenitor fate. [PDF]

Sci Immunol
Zhao X, Hu SS, Lee WH, Zakrzewski JL, Mi QS, Rosenstein RK, Zang C, Ma X, Xue HH.   +8 more
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Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status. [PDF]

J Extracell Biol
Leyk S, Liebold I, Lanzloth C, Richardt U, Kux JM, Kilian C, Moritz M, Gocke A, Meyer S, Höhn K, Honecker B, Haas H, Böttcher M, Weidemann S, Kind S, Schlüter H, Metwally NG, Adlung L, Sáez PJ, Jacobs T, Ruckdeschel K, Bosurgi L.   +21 more
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Thymocyte Apoptosis

Journal of Clinical Immunology, 1999
Apoptosis is the fate of most thymocytes. Many molecules participate in the decision of whether a thymocyte is to live or to die, including cell surface receptors, such as the T cell receptor for antigen, Notch-1, and costimulatory receptors, ligand-regulated nuclear transcription factors such as the glucocorticoid receptor, signaling, and effector ...
Y, Yang, J D, Ashwell
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Thymocytes Positively Select Thymocytes in Human System

Human Immunology, 1997
We previously demonstrated the expression of MHC class II molecules in a significant percentage of human fetal and postnatal thymocytes. These results, at that time, raised the question as to whether the MHC class II molecules on immature thymocytes could actively be involved in the selection of immature T cells.
E Y, Choi, W S, Park, K C, Jung, D H, Chung, Y M, Bae, T J, Kim, H G, Song, S H, Kim, D I, Ham, J H, Hahn, J, Kim, K, Kim, T S, Hwang, S H, Park   +13 more
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Thymocyte transformation enhanced

Nature Medicine, 2014
A new study identifies recurrent somatic duplications of a NOTCH1-driven enhancer of MYC in human T cell leukemia. This enhancer is required for both normal and malignant T cell development.
Gayle P, Pouliot, Alejandro, Gutierrez
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Antibodies in Thymocytes

Nature, 1963
FRAGRAEUS was not able to show plasmocytes in normal thymus1 ; nor did she find plasmocytes in thymus after antigen injections2. After removal of the thymus in adult rats the antibody production is unchanged3. In spite of these results which ascribe no important influence on antibody production by the thymus there are still several clinical signs which
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Thymocyte Egress

Science, 2010
Cells that ensheath blood vessels promote exit of the developing T lymphocytes from the thymus.
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Positive Selection of Thymocytes

Annual Review of Immunology, 1995
Differentiation of αβ T cell receptor (TCR)-expressing T cells involves an obligatory interaction with self-major histocompatibility complex (MHC) molecules in the thymus. This process, called positive selection, both rescues thymocytes from programmed cell death and induces their differentiation into mature T cells.
S C, Jameson, K A, Hogquist, M J, Bevan
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LDH analysis of human thymocytes and thymocyte subsets.

The Journal of Immunology, 1984
Abstract The lactate dehydrogenase (LDH) isoenzyme pattern (expressed as the B:A subunit ratio) and two enzymes of the purine metabolism adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) (expressed as the ADA/PNP ratio) were studied in human prenatal thymocytes, in subsets of human infant thymocytes, and in peripheral T
J R, Plum, M, De Smedt, L J, Sabbe, J E, De Roose   +3 more
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