Results 1 to 10 of about 304,787 (301)

The Role of Proteasomes in the Thymus

Frontiers in Immunology, 2021
The thymus provides a microenvironment that supports the generation and selection of T cells. Cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells (mTECs) are essential components of the thymic microenvironment and present MHC ...
Melina Frantzeskakis, Yousuke Takahama, Izumi Ohigashi   +2 more
doaj   +1 more source

Thymus transplantation [PDF]

Clinical Immunology, 2010
Thymus transplantation is a promising investigational therapy for infants born with no thymus. Because of the athymia, these infants lack T cell development and have a severe primary immunodeficiency. Although thymic hypoplasia or aplasia is characteristic of DiGeorge anomaly, in "complete" DiGeorge anomaly, there is no detectable thymus as determined ...
M Louise, Markert, Blythe H, Devlin, Elizabeth A, McCarthy   +2 more
openaire   +2 more sources

Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials

Journal of Immunology Research, 2022
Objective. To assess the clinical efficacy of flavonoid supplements on allergic diseases. Design. Systematic review. Data Sources. MEDLINE/PubMed, Scopus, Web of Science, and Embase databases were searched from inception to September 2021.
Poliana Guiomar de Almeida Brasiel, Fernanda Verdini Guimarães, Patrícia Machado Rodrigues, Dumith Chequer Bou-Habib, Vinicius de Frias Carvalho   +4 more
doaj   +1 more source

Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

Frontiers in Immunology, 2020
One of the main consequences of thymus aging is the decrease in naïve T cell output. This condition accelerates at the onset of puberty, and presents as a major clinical complication for cancer patients who require cytoablative therapy. Specifically, the
Michael Ly Hun, Kahlia Wong, Josephine Rahma Gunawan, Abdulaziz Alsharif, Kylie Quinn, Ann P. Chidgey   +5 more
doaj   +1 more source

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

Frontiers in Endocrinology, 2020
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions.
Ygor Parladore Silva, Andressa Bernardi, Rudimar Luiz Frozza   +2 more
doaj   +1 more source

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

Skeletal Muscle, 2017
Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González, Wallace de Mello, Gillian S. Butler-Browne, Suse Dayse Silva-Barbosa, Vincent Mouly, Wilson Savino, Ingo Riederer   +6 more
doaj   +1 more source

Zika virus infects human blood mononuclear cells

BMC Infectious Diseases, 2019
Background Zika virus (ZIKV) infection gained public health concern after the 2015 outbreak in Brazil, when microcephaly rates increased in babies born from infected mothers.
Carolina V. Messias, Julia P. Lemos, Daniela P. Cunha, Zilton Vasconcelos, Lidiane M. S. Raphael, Myrna C. Bonaldo, Bruno Cister-Alves, Dumith Chequer Bou-Habib, Vinicius Cotta-de-Almeida, Wilson Savino, Daniella A. Mendes-da-Cruz   +10 more
doaj   +1 more source

Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery

Frontiers in Endocrinology, 2018
Maintenance of thymus homeostasis is a delicate interplay involving hormones, neurotransmitters and local microenvironmental proteins, as well as saccharides, acting on both thymocytes and stromal cells.
Ednéa Oliveira-de-Abreu, Danielle Silva-dos-Santos, Ailin Lepletier, Tiago D. P. Ramos, Rafaella Ferreira-Reis, Larissa Vasconcelos-Fontes, Mariana T. Ramos, Mariana T. Ramos, Rafael C. Torres, Vinícius Cotta-de-Almeida, Vinícius Cotta-de-Almeida, Vinícius de Frias Carvalho, Vinícius de Frias Carvalho, Déa M. S. Villa-Verde, Déa M. S. Villa-Verde   +14 more
doaj   +1 more source

Aspectos subjetivos do morar e trabalhar na mesma comunidade: a realidade vivenciada pelo agente comunitário de saúde

Interface: Comunicação, Saúde, Educação, 2009
O Agente Comunitário de Saúde (ACS) é o elo entre comunidade e sistema de saúde no Programa Saúde da Família (PSF), sendo o único trabalhador que obrigatoriamente reside na comunidade onde trabalha.
Tatiana de Andrade Jardim, Selma Lancman
doaj   +1 more source

Dynamics of Lymphocyte Populations during Trypanosoma cruzi Infection: From Thymocyte Depletion to Differential Cell Expansion/Contraction in Peripheral Lymphoid Organs

Journal of Tropical Medicine, 2012
The comprehension of the immune responses in infectious diseases is crucial for developing novel therapeutic strategies. Here, we review current findings on the dynamics of lymphocyte subpopulations following experimental acute infection by Trypanosoma ...
Alexandre Morrot, Juliana Barreto de Albuquerque, Luiz Ricardo Berbert, Carla Eponina de Carvalho Pinto, Juliana de Meis, Wilson Savino   +5 more
doaj   +1 more source