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The Effects of Maternal Subclinical Hypothyroidism on Fetal Thymus Size: A Prospective Study. [PDF]
Objective: This study investigated the impact of maternal subclinical hypothyroidism on fetal thymus size and development and explored how inadequate thyroid hormone production in pregnant women affects the fetal thymus. Methods: Conducted at the Giresun
Albayrak M, Yükcü B.
europepmc +2 more sources
Asymptomatic neck mass and normal variations of the thymus in children: A report of two cases from a tertiary hospital in Riyadh, Saudi Arabia. [PDF]
The pathogenesis of cervical extension of the thymus has been postulated to be incomplete descent of the thymus in the midline of the neck, which is considered normal in children.
Albaqami M, Almonifi A, Albelali A.
europepmc +2 more sources
AbstractThe thymus prevents autoimmune diseases through mechanisms that operate in the cortex and medulla, comprising positive and negative selection and the generation of regulatory T-cells (Tregs). Egress from the thymus through the perivascular space (PVS) to the blood is another possible checkpoint, as shown by some autoimmune/immunodeficiency ...
Yosuke Yamada+7 more
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Adenosine is an ancient extracellular signaling molecule that regulates various biological functions via activating four G-protein-coupled receptors, A1, A2A, A2B, and A3 adenosine receptors. As such, several studies have highlighted a role for adenosine signaling in affecting the T cell development in the thymus. Recent studies indicate that adenosine
Krisztina Köröskényi+5 more
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The Role of Proteasomes in the Thymus
The thymus provides a microenvironment that supports the generation and selection of T cells. Cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells (mTECs) are essential components of the thymic microenvironment and present MHC ...
Melina Frantzeskakis+2 more
doaj +1 more source
One of the main consequences of thymus aging is the decrease in naïve T cell output. This condition accelerates at the onset of puberty, and presents as a major clinical complication for cancer patients who require cytoablative therapy. Specifically, the
Michael Ly Hun+5 more
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Application of 2D-ultrasonography in prenatal assessment of fetal thymus development [PDF]
Objective: To investigate the value of prenatal ultrasound measurement of thymus size and to determine whether maternal administration of euthyrox affects fetal thymus development.
YANG Tian, JI Xiang, NIU Jianmei, KONG Xiaoxiao, LV Mingli
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The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions.
Ygor Parladore Silva+2 more
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Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials
Objective. To assess the clinical efficacy of flavonoid supplements on allergic diseases. Design. Systematic review. Data Sources. MEDLINE/PubMed, Scopus, Web of Science, and Embase databases were searched from inception to September 2021.
Poliana Guiomar de Almeida Brasiel+4 more
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Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González+6 more
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