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The Role of Proteasomes in the Thymus
Frontiers in Immunology, 2021 The thymus provides a microenvironment that supports the generation and selection of T cells. Cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells (mTECs) are essential components of the thymic microenvironment and present MHC ...
Melina Frantzeskakis +2 more
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Clinical Immunology, 2010 Thymus transplantation is a promising investigational therapy for infants born with no thymus. Because of the athymia, these infants lack T cell development and have a severe primary immunodeficiency. Although thymic hypoplasia or aplasia is characteristic of DiGeorge anomaly, in "complete" DiGeorge anomaly, there is no detectable thymus as determined ...
M Louise, Markert +2 more
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Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials
Journal of Immunology Research, 2022 Objective. To assess the clinical efficacy of flavonoid supplements on allergic diseases. Design. Systematic review. Data Sources. MEDLINE/PubMed, Scopus, Web of Science, and Embase databases were searched from inception to September 2021.
Poliana Guiomar de Almeida Brasiel +4 more
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Frontiers in Immunology, 2020 One of the main consequences of thymus aging is the decrease in naïve T cell output. This condition accelerates at the onset of puberty, and presents as a major clinical complication for cancer patients who require cytoablative therapy. Specifically, the
Michael Ly Hun +5 more
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The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
Frontiers in Endocrinology, 2020 A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions.
Ygor Parladore Silva +2 more
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Skeletal Muscle, 2017 Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González +6 more
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Developmental and Anatomical Patterns Of IL-2 Gene Expression in Vivo in The Murine Thymus [PDF]
, 1993 Interleukin-2 (IL-2) is a potent growth factor that mature T lymphocytes synthesize and use as a proliferation signal. Much controversy has arisen concerning whether it is used to drive the extensive proliferation of immature pre-T cells in the thymus ...
Rothenberg, Ellen V. +1 more
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Zika virus infects human blood mononuclear cells
BMC Infectious Diseases, 2019 Background Zika virus (ZIKV) infection gained public health concern after the 2015 outbreak in Brazil, when microcephaly rates increased in babies born from infected mothers.
Carolina V. Messias +10 more
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Frontiers in Endocrinology, 2018 Maintenance of thymus homeostasis is a delicate interplay involving hormones, neurotransmitters and local microenvironmental proteins, as well as saccharides, acting on both thymocytes and stromal cells.
Ednéa Oliveira-de-Abreu +14 more
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The essential oil of Thymbra capitata and its application as a biocide on stone and derived surfaces [PDF]
, 2019 Many chemicals used nowadays for the preservation of cultural heritage pose a risk to both human health and the environment. Thus, it is desirable to find new and eco-friendly biocides that can replace the synthetic ones.
Bruno M. +4 more
core +1 more source