Results 21 to 30 of about 304,787 (301)

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Oral Versus Intragastric Inoculation: Similar Pathways of Trypanosoma cruzi Experimental Infection? From Target Tissues, Parasite Evasion, and Immune Response

Frontiers in Immunology, 2018
Currently, oral infection is the most frequent transmission mechanism of Chagas disease in Brazil and others Latin American countries. This transmission pathway presents increased mortality rate in the first 2 weeks, which is higher than the calculated ...
Juliana Barreto de Albuquerque, Danielle Silva dos Santos, Jens V. Stein, Juliana de Meis, Juliana de Meis   +4 more
doaj   +1 more source

Improving thymus implantation for congenital athymia with interleukin‐7

Clinical & Translational Immunology, 2023
Objectives Thymus implantation is a recently FDA‐approved therapy for congenital athymia. Patients receiving thymus implantation develop a functional but incomplete T cell compartment.
Hyunjung Min, Laura A Valente, Li Xu, Shane M O'Neil, Lauren R Begg, Joanne Kurtzberg, Anthony J Filiano   +6 more
doaj   +1 more source

A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation

eLife, 2021
Ataxia Telangiectasia (A-T) and Ataxia with Ocular Apraxia Type 1 (AOA1) are devastating neurological disorders caused by null mutations in the genome stability genes, A-T mutated (ATM) and Aprataxin (APTX), respectively.
Harvey Perez, May F Abdallah, Jose I Chavira, Angelina S Norris, Martin T Egeland, Karen L Vo, Callan L Buechsenschuetz, Valentina Sanghez, Jeannie L Kim, Molly Pind, Kotoka Nakamura, Geoffrey G Hicks, Richard A Gatti, Joaquin Madrenas, Michelina Iacovino, Peter J McKinnon, Paul J Mathews   +16 more
doaj   +1 more source

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone [PDF]

, 1975
The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by
Baltimore, David, Kung, Patrick C., McCaffrey, Ronald P., Silverstone, Allen E.   +3 more
core   +1 more source

Oral Route Driven Acute Trypanosoma cruzi Infection Unravels an IL-6 Dependent Hemostatic Derangement

Frontiers in Immunology, 2019
Oral transmission of Trypanosoma cruzi, the etiologic agent of Chagas disease, is presently the most important route of infection in Brazilian Amazon.
Dina Antunes, Dina Antunes, Alessandro Marins-Dos-Santos, Alessandro Marins-Dos-Santos, Mariana Tavares Ramos, Mariana Tavares Ramos, Barbara Angelica S. Mascarenhas, Barbara Angelica S. Mascarenhas, Carlos José de Carvalho Moreira, Désio Aurélio Farias-de-Oliveira, Désio Aurélio Farias-de-Oliveira, Wilson Savino, Wilson Savino, Robson Q. Monteiro, Juliana de Meis, Juliana de Meis   +15 more
doaj   +1 more source

The Neuropeptides Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Control HIV-1 Infection in Macrophages Through Activation of Protein Kinases A and C

Frontiers in Immunology, 2018
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are highly similar neuropeptides present in several tissues, endowed with immunoregulatory functions and other systemic effects.
Jairo R. Temerozo, Jairo R. Temerozo, Suwellen S. D. de Azevedo, Daniella B. R. Insuela, Rhaíssa C. Vieira, Pedro L. C. Ferreira, Vinícius F. Carvalho, Vinícius F. Carvalho, Gonzalo Bello, Dumith Chequer Bou-Habib, Dumith Chequer Bou-Habib   +10 more
doaj   +1 more source

Mediterranean Fin Whales (Balaenoptera physalus) Threatened by Dolphin MorbilliVirus [PDF]

, 2015
During 2011-2013, dolphin morbillivirus was molecularly identified in 4 stranded fin whales from the Mediterranean Sea. Nucleoprotein, phosphoprotein, and hemagglutinin gene sequences of the identified strain were highly homologous with those of a ...
BEFFAGNA, GIORGIA, Casalone, Cristina, CENTELLEGHE, CINZIA, Cocumelli, Cristiano, Denurra, Daniele, Di Francesco, Cristina Esmeralda, Di Guardo, Giovanni, MAZZARIOL, SANDRO, Pautasso, Alessandra, Pintore, Antonio, Povinelli, Michele, Terracciano, Giuliana   +11 more
core   +3 more sources

The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). [PDF]

, 2015
Cell number in the mouse thymus increases steadily during the first two weeks after birth. It then plateaus and begins to decline by seven weeks after birth. The factors governing these dramatic changes in cell production are not well understood.
Berent-Maoz, Beata, Casero, David, Crooks, Gay M, Dorshkind, Kenneth, Fice, Michael, Lowry, William, Montecino-Rodriguez, Encarnacion, Seet, Christopher S   +7 more
core   +3 more sources

Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates? [PDF]

, 2018
In teleosts, as in mammals, the immune system is tightly regulated by sexual steroid hormones, such as oestrogens. We investigated the effects of 17β-oestradiol on the expression of several genes related to T cell development and resulting T cell ...
Duflot, Aurélie, Farcy, Emilie, Knigge, Thomas, Monsinjon, Tiphaine, Paiola, Matthieu, Pinto, Patricia IS   +5 more
core   +3 more sources