Results 71 to 80 of about 163,535 (332)
Advanced Science, EarlyView.Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang +13 more
wiley +1 more source
Generation and Regeneration of Thymic Epithelial Cells
Frontiers in Immunology, 2020 The thymus is unique in its ability to support the maturation of phenotypically and functionally distinct T cell sub-lineages. Through its combined production of MHC-restricted conventional CD4+ and CD8+, and Foxp3+ regulatory T cells, as well as non ...
Abdullah S. Alawam +2 more
doaj +1 more source
When few survive to tell the tale: thymus and gonad as auditioning organs: historical overview [PDF]
arXiv, 2018 Unlike other organs, the thymus and gonads generate non-uniform cell populations, many members of which perish, and a few survive. While it is recognized that thymic cells are 'audited' to optimize an organism's immune repertoire, whether gametogenesis could be orchestrated similarly to favour high quality gametes is uncertain.
arxiv
Application of humanized mice in the safety experiments of antibody drugs
Animal Models and Experimental Medicine, EarlyView.The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun +9 more
wiley +1 more source
Estimate of genetic variants using CNV‐Seq for fetuses with oligohydramnios or polyhydramnios
Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023 The overall detection rate of clinically significant findings was 8%, with 5.0% in the isolated group and 11.0% in non‐isolated group. Non‐isolated group especially oligohydramnios subgroup is inclined to obtained more pathogenicity genetic anomalies and to terminate their pregnancy outcome.
Panlai Shi +5 more
wiley +1 more source
Molecules, 2009 The volatile constituents of the aerial parts of two samples of Thymus longicaulis C. Presl, collected in Campania and in Sicily, and two samples of Thymus pulegioides L.
Felice Senatore +6 more
doaj +1 more source
Electrons on the double helix: optical experiments on native DNA [PDF]
arXiv, 2001 Optical experiments on calf thymus DNA films subjected to different buffer environments are reported. The optical conductivity is that of a disordered or lightly doped semiconductor with a well-defined band-gap for charge excitations and low frequency transport determined by a small number of strongly localized electron states.
arxiv
Animal Research and One Health, EarlyView.Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen +6 more
wiley +1 more source
Molecular Reproduction and Development, Volume 89, Issue 12, Page 597-607, December 2022., 2022 Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The DRB1 locus is strongly associated with both susceptibility and resistance to rheumatoid arthritis (RA). DRB1 alleles encoding the VKA or VRA epitope in positions 11, 71, and 74 confer the highest risk of developing RA, whereas the allele encoding VEA is protective.
Vibha Jha +10 more
wiley +1 more source