Results 101 to 110 of about 33,818 (248)
Detection of Tie2 Cell-Associated Endodomain.
, 2013 A Cells were incubated with PMA for the times indicated in hours before cell lysis and detection of cellular Tie1 endodomain by immunoblotting with an antibody recognizing Tie1 carboxy-terminus, as indicated.
Tania M. Hansen (336147) +3 more
core +1 more source
Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis. [PDF]
PLoS ONE, 2016 Primary myelofibrosis (PMF) is a Philadelphia-negative (Ph-) myeloproliferative disorder, showing abnormal CD34+ progenitor cell trafficking, splenomegaly, marrow fibrosis leading to extensive extramedullary haematopoiesis, and abnormal neoangiogenesis ...
Rita Campanelli +17 more
doaj +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Analysis of Tie2 function in mast cells [PDF]
Allergy, Asthma & Clinical Immunology, 2010 BackgroundMast cells are most widely acknowledged as a centralmediator of allergic reactions. Recent literature has alsoimplicated mast cells in a variety of biological andpathological conditions, spurring an interest in thegenetic regulation of mast cell function and develop-ment.
Hirukawa Alison +4 more
openaire +2 more sources
Cell Communication and Signaling, 2020 Background Venous malformations (VMs), most of which associated with activating mutations in the endothelial cells (ECs) tyrosine kinase receptor TIE2, are characterized by dilated and immature veins with scarce smooth muscle cells (SMCs) coverage ...
Yameng Si +7 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi +18 more
wiley +1 more source
, 2007 A critical role for Tie1, an orphan endothelial receptor, in blood vessel morphogenesis has emerged from mutant mouse studies. Moreover, it was recently demonstrated that certain angiopoietin (Ang) family members can activate Tie1.
Sukhatme, Vikas P. +19 more
core +1 more source
Circulating markers of the endothelial angiopoietin/Tie2 system.
, 2023 Circulating levels of angiopoietin-1 (A), angiopoietin-2 (B), angiopoietin-2/1 ratio (C) and soluble Tie2 (D) in plasma of Tie2+/+ male (white bars), Tie2+/+ female (grey bars), Tie2+/- male (striped white bars) and Tie2+/- female (striped grey bars ...
Anoek L. I. van Leeuwen (8839811) +8 more
core +1 more source
Investigative Ophthalmology and Visual Science, 2020 Purpose Tyrosine kinase with immunoglobulin-like and EGF-like domains 2 (Tie2) activation in Schlemm's canal (SC) endothelium is required for the maintenance of IOP, making the angiopoietin/Tie2 pathway a target for new and potentially disease modifying ...
Guorong Li +13 more
semanticscholar +1 more source
Diabetes & Vascular Disease Research, 2021 Background: Insulin exerts vasculoprotective effects on endothelial cells (ECs) and growth-promoting effects on vascular smooth muscle cells (SMCs) in vitro, and suppresses neointimal growth in vivo.
Yusaku Mori +8 more
doaj +1 more source