Results 41 to 50 of about 33,818 (248)
Experimental and Molecular Medicine, 2023 Tumor progression is intimately associated with the vasculature, as tumor proliferation induces angiogenesis and tumor cells metastasize to distant organs via blood vessels. However, whether tumor invasion is associated with blood vessels remains unknown.
Eunhyeong Lee +17 more
semanticscholar +1 more source
Theranostics, 2021 Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis is tightly coordinated during bone development. However, the molecular regulators of intercellular communication in the bone microenvironment are not well studied ...
Jyotirmaya Behera +3 more
semanticscholar +1 more source
Elucidating the effect of deferoxamine, a hypoxia mimetic agent, on angiogenesis restoration in endothelial progenitor cells (EPCs) from diabetic mice [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Diabetes increases the risk of heart disease and stroke, primarily through endothelial cell dysfunction and vascular damage. These vascular complications are partly due to defects in endothelial progenitor cells (EPCs).
Vahid Siavashi +4 more
doaj +1 more source
Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. [PDF]
PLoS ONE, 2014 Reports demonstrate the role of M-CSF (CSF1) in tumor progression in mouse models as well as the prognostic value of macrophage numbers in breast cancer patients.
Mary A Forget +10 more
doaj +1 more source
Cancer Research, 2022 Multiple preclinical tumor models, cell stimulation experiments, and meta-analysis of published tumor single cell RNA sequencing data challenge the reported role of Tie2-positive macrophages for tumor angiogenesis, metastasis, and relapse after ...
Moritz Jakab +4 more
semanticscholar +1 more source
Клиническая онкогематология, 2014 This review focuses on association between the selectivity of Bcr-Abl kinase inhibitors and the spectrum of their adverse effects during treatment of patients with chronic myeloid leukemia.
A. A. Zeifman +3 more
doaj +1 more source
The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling. [PDF]
PLoS ONE, 2012 Angiopoietin-1 (Ang1) signals via the receptor tyrosine kinase Tie2 which exists in complex with the related protein Tie1 at the endothelial cell surface.
Harprit Singh +3 more
doaj +1 more source
Periodontal diseases and adverse pregnancy outcomes. Present and future
Periodontology 2000, EarlyView., 2023 Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis +3 more
wiley +1 more source
Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism
Biology Open, 2014 In this study, we have identified a novel member of the AMPK family, namely Sucrose non-fermenting related kinase (Snrk), that is responsible for maintaining cardiac metabolism in mammals. SNRK is expressed in the heart, and brain, and in cell types such
Stephanie M. Cossette +16 more
doaj +1 more source
bioRxiv, 2022 Objective Vascular growth followed by vessel specification is crucial for the establishment of a hierarchical blood vascular network. We have here investigated mechanisms underlying venogenesis, particularly the molecular control over venous fate ...
Xudong Cao +17 more
semanticscholar +1 more source