Results 41 to 50 of about 21,607 (116)

Resistance mechanisms of tigecycline in Acinetobacter baumannii

Frontiers in Cellular and Infection Microbiology, 2023
Acinetobacter baumannii is widely distributed in nature and in hospital settings and is a common pathogen causing various infectious diseases. Currently, the drug resistance rate of A.
Chunli Sun, Yunsong Yu, Yunsong Yu, Yunsong Yu, Xiaoting Hua, Xiaoting Hua, Xiaoting Hua, Xiaoting Hua   +7 more
doaj   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, Volume 13, Issue 16, 18 March 2026.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

When Antibiotics Leave a Mark: Minocycline‐Induced Hyperpigmentation

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Bluish discoloration of the dorsal aspects of the hands and nails. ABSTRACT This article presents two patients with significant minocycline‐induced hyperpigmentation, illustrating the diverse clinical manifestations across various body sites. Judicious use of minocycline and early recognition of its adverse effects are crucial to reduce the risk of ...
Clarissa Ting, Benjamin S. Daniel, Timothy O'Brien, Aaron J. Robinson   +3 more
wiley   +1 more source

Polymicrobial Pasteurella multocida‐Anaerobic Coinfection Followhing a Cat Bite: Limb Salvage Through Metagenomic Next‐Generation Sequencing‐Guided Diagnosis and Multidisciplinary Management

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Successful management of a Pasteurella multocida and polymicrobial infection following a cat bite on the left leg entailed debridement, split‐thickness skin grafting with vacuum‐sealing drainage, and targeted antibiotic treatment. This approach enabled successful incorporation of the skin graft, preserving the limb and eliminating the ...
Yuanqing Qu, Yuan Liu, Xin Zhou, Pengjie Xu, Lu Wang   +4 more
wiley   +1 more source

Over expression of AdeABC and AcrAB-TolC efflux systems confers tigecycline resistance in clinical isolates of Acinetobacter baumannii and Klebsiella pneumoniae

Revista da Sociedade Brasileira de Medicina Tropical, 2016
: INTRODUCTION: Due to the wide use of tigecycline in the treatment of severe infections caused by multidrug-resistant (MDR) bacteria, clinical resistance to tigecycline has increased in recent years.
Yin Yuhan, Yue Ziyun, Zhang Yongbo, Li Fuqiang, Zhang Qinghua   +4 more
doaj   +1 more source

Gastric Microbiome Alterations in Sepsis‐Related Gastrointestinal Bleeding: Two Case Reports and Literature Review

JGH Open, Volume 10, Issue 3, March 2026.
ABSTRACT Sepsis, characterized by life‐threatening organ dysfunction resulting from an uncontrolled response to infection, can impact various systems of the body, including the digestive system. Prior research has identified sepsis as a significant risk factor for gastrointestinal bleeding.
Fangjie Fu, Chen Zhang, Zhengying Xu, Peng Ji, Zhongwei Zhang   +4 more
wiley   +1 more source

The Rapid Emergence of Tigecycline Resistance in blaKPC–2 Harboring Klebsiella pneumoniae, as Mediated in Vivo by Mutation in tetA During Tigecycline Treatment

Frontiers in Microbiology, 2018
Tigecycline is one of the last resort treatments for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Tigecycline resistance often occurs during the clinical treatment of CRKP, yet its mechanism has still not been clearly elucidated.
Xiaoxing Du, Fang He, Qiucheng Shi, Feng Zhao, Juan Xu, Ying Fu, Yunsong Yu   +6 more
doaj   +1 more source

Prevalence of Meningitis Among Neonates With Sepsis: Analysis of Predictors at a Tertiary Care Hospital in Bangladesh

Reproductive, Female and Child Health, Volume 5, Issue 1, March 2026.
ABSTRACT Objective To identify the prevalence of neonatal meningitis and to describe the clinical, haematological and bacteriological profiles of neonatal sepsis and meningitis. This study also aimed to identify the factors predictive of meningitis among neonates with sepsis.
Syeda Humaida Hasan, Humayra Akter, Jagadish C. Das, Adrita Das   +3 more
wiley   +1 more source

Isoniazid potentiates tigecycline to kill methicillin-resistant Staphylococcus aureus

Emerging Microbes and Infections
Therapeutic option for treating methicillin-resistant Staphylococcus aureus (MRSA) infection is urgently required since its resistance to a broad spectrum of currently available antibiotics.
Xuan-wei Chen, Hao-qing Chen, Jia-han Wu, Zhi-han Wang, Yu-Qing Zhou, Si-qi Tian, Bo Peng   +6 more
doaj   +1 more source

Tigecycline for severe Clostridium difficile infection

International Journal of Infectious Diseases, 2014
Limited data suggest that tigecycline may be of value in the treatment of Clostridiumdifficile infection. We reviewed our experience using tigecycline to treat severe c.
Ashley Thomas, Farhan Khan, Nizam Uddin, Mark R. Wallace   +3 more
doaj   +1 more source