Results 31 to 40 of about 26,995 (192)

In vitro and in vivo antibacterial activity of tigecycline against Vibrio vulnificus

Journal of Microbiology, Immunology and Infection, 2018
Background/purpose: The aim of this study is to investigate the role of tigecycline in Vibrio vulnificus infection. Methods: Eight randomly selected clinical V.
Hung-Jen Tang, Chi-Chung Chen, Chih-Cheng Lai, Chun-Cheng Zhang, Tzu-Chieh Weng, Yu-Hsin Chiu, Han-Siong Toh, Shyh-Ren Chiang, Wen-Liang Yu, Wen-Chien Ko, Yin-Ching Chuang   +10 more
doaj   +1 more source

Mechanism of Abnormal Coagulation Induced by Tigecycline in Cancer Patients

Frontiers in Pharmacology, 2022
Tigecycline is a broad-spectrum active intravenous antibiotic that is active against methicillin-resistant staphylococcus aureus. In Phase 3 and 4 clinical trials, increased all-cause mortality was observed in patients treated with tigecycline compared ...
Li-Hua Sun, Kun-Hao Bai, Kun-Hao Bai, Guo-Yan Wu, Xiao-Peng Tian, Zhi-Qing Zou, Da-Wei Wang, Yu-Jun Dai, Yu-Jun Dai, Si-Liang Chen   +9 more
doaj   +1 more source

DataSheet_1_A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae.docx

, 2022
The increasing incidence of tigecycline resistance undoubtedly constitutes a serious threat to global public health. The combination therapies had become the indispensable strategy against this threat. Herein, 11 clinical tigecycline-resistant Klebsiella
Lang Sun (1688164), Xiukun Wang (6807905), Lilan Sun (5074193), Xinxin Hu (429652), Youwen Zhang (4019408), Xuefu You (429654), Xue Li (285380), Tongying Nie (9539016)   +7 more
core   +1 more source

Systematic evaluation and Meta-analysis of the efficacy and safety of different doses of tigecycline in ventilator-associated pneumonia caused by multiple resistant bacteria

, 2023
Introduction Ventilator-associated pneumonia (VAP) caused by multi-resistant bacteria is a serious complication in hospitalized patients. Tigecycline, a broad-spectrum antibiotic, has been suggested as a potential treatment option for this condition, but
Junlin L u, Changwen Feng, Qingming Mo, Wendian Zhu, Xiaoshan Yang, Zhaoxu Cai, Junlin Lu   +6 more
core   +1 more source

Tigecycline: its potential for treatment of brucellosis

, 2007
The in vitro efficacy and synergistic activity of tigecycline in comparison with other antimicrobials used in brucellosis, were tested for 16 Brucella melitensis strains by the E-test method.
MURAT DİZBAY
core   +2 more sources

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae

Annals of Clinical Microbiology and Antimicrobials
Background Heteroresistance can lead to treatment failure and has brought a rigorous challenge to clinical laboratories for detecting them. The aim of this study was to investigate the potential for tigecycline-susceptible Klebsiella pneumoniae (K ...
Qiaoyu Zhang, Linwen Zheng, Lirong Wen, Shanshan Li, Yuli Nie, Jiansen Chen   +5 more
doaj   +1 more source

Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells

Journal of Translational Medicine, 2023
Background Despite recent advances in locoregional, systemic, and novel checkpoint inhibitor treatment, hepatocellular carcinoma (HCC) is still associated with poor prognosis.
Dominik T. Koch, Haochen Yu, Iris Beirith, Malte Schirren, Moritz Drefs, Yunfei Liu, Mathilda Knoblauch, Dionysios Koliogiannis, Weiwei Sheng, Enrico N. De Toni, Alexandr V. Bazhin, Bernhard W. Renz, Markus O. Guba, Jens Werner, Matthias Ilmer   +14 more
doaj   +1 more source

Identification of Novel tet(X3) Variants Resistant To Tigecycline in Acinetobacter Species

Microbiology Spectrum, 2022
The emergence of the tet(X) gene is a severe challenge to global public health security, as clinical tigecycline resistance shows a rapidly rising trend. In this research, we identified two tigecycline-resistant Acinetobacter sp. strains containing seven
Yumeng Cheng, Yakun Li, Runhao Yu, Mingxiang Ma, Meng Yang, Hongbin Si   +5 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source