Results 31 to 40 of about 28,714 (188)

Prevalence and risk factors of tigecycline-induced liver injury: A multicenter retrospective study

open access: yesInternational Journal of Infectious Diseases, 2022
: Objective: We conducted this multicenter retrospective study to evaluate the prevalence, clinical patterns, and risk factors for tigecycline-induced liver injury, which is a type of drug-induced liver injury (DILI).
Zhenwei Yu   +5 more
doaj   +1 more source

Induction of Tigecycline Resistance in Acinetobacter baumannii

open access: yesBio-Protocol, 2014
Multidrug resistance Acinetobacter baumannii (A. baumannii) (MDRAB) has emerged as a serious threat in hospitals in recent years. Currently, there are few antibiotics, including tigecycline, available to treat infections caused by MDRAB effectively. Both
Ming-Feng Lin, Yun-You Lin, Chung-Yu Lan
doaj   +1 more source

Tigecycline Interferes with Fibrinogen Polymerization Independent of Peripheral Interactions with the Coagulation System

open access: yesAntibiotics, 2020
Tigecycline offers broad anti-bacterial coverage for critically ill patients with complicated infections. A described but less researched side effect is coagulopathy.
Anna Brandtner   +9 more
doaj   +1 more source

Characterization of Tigecycline-Heteroresistant Klebsiella pneumoniae Clinical Isolates From a Chinese Tertiary Care Teaching Hospital

open access: yesFrontiers in Microbiology, 2021
Tigecycline has been used as one of the therapeutic choices for the treatment of infections caused by multidrug-resistant Klebsiella pneumoniae. However, the emergence of tigecycline heteroresistance has led to great challenges in treating these ...
Qiaoyu Zhang   +3 more
doaj   +1 more source

In vitro and in vivo antibacterial activity of tigecycline against Vibrio vulnificus

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Background/purpose: The aim of this study is to investigate the role of tigecycline in Vibrio vulnificus infection. Methods: Eight randomly selected clinical V.
Hung-Jen Tang   +10 more
doaj   +1 more source

Mechanism of Abnormal Coagulation Induced by Tigecycline in Cancer Patients

open access: yesFrontiers in Pharmacology, 2022
Tigecycline is a broad-spectrum active intravenous antibiotic that is active against methicillin-resistant staphylococcus aureus. In Phase 3 and 4 clinical trials, increased all-cause mortality was observed in patients treated with tigecycline compared ...
Li-Hua Sun   +9 more
doaj   +1 more source

DataSheet_1_A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae.docx

open access: yes, 2022
The increasing incidence of tigecycline resistance undoubtedly constitutes a serious threat to global public health. The combination therapies had become the indispensable strategy against this threat. Herein, 11 clinical tigecycline-resistant Klebsiella
Lang Sun (1688164)   +7 more
core   +1 more source

Tigecycline: its potential for treatment of brucellosis

open access: yes, 2007
The in vitro efficacy and synergistic activity of tigecycline in comparison with other antimicrobials used in brucellosis, were tested for 16 Brucella melitensis strains by the E-test method.
MURAT DİZBAY
core   +2 more sources

Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells

open access: yesJournal of Translational Medicine, 2023
Background Despite recent advances in locoregional, systemic, and novel checkpoint inhibitor treatment, hepatocellular carcinoma (HCC) is still associated with poor prognosis.
Dominik T. Koch   +14 more
doaj   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki   +3 more
wiley   +1 more source

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