Results 11 to 20 of about 28,714 (188)

Tigecycline for severe Clostridium difficile infection [PDF]

open access: yesInternational Journal of Infectious Diseases, 2014
Limited data suggest that tigecycline may be of value in the treatment of Clostridiumdifficile infection. We reviewed our experience using tigecycline to treat severe c.
Mark R Wallace, Nizam Uddin
exaly   +4 more sources

Tigecycline

open access: yesJournal of Postgraduate Medicine, 2009
Infection with resistant pathogens can adversely affect clinical, microbiological and economic outcomes. New agents for the treatment of many such serious infections are acutely needed in hospital practice. Tigecycline is a novel glycylcycline antimicrobial for intravenous use.
Bhattacharya, M., Parakh, A., Narang, M.
core   +7 more sources

Tigecycline Heteroresistance and Resistance Mechanism in Clinical Isolates of Acinetobacter baumannii

open access: yesMicrobiology Spectrum, 2021
Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In this study, we investigated tigecycline heteroresistance in A.
Kwan Soo Ko
exaly   +3 more sources

Five-Years Tigecycline Experience an Analysis of Real-Life Data [PDF]

open access: yesHaseki Tıp Bülteni, 2018
Aim: Tigecycline has been approved by the Food and Drug Administration for the treatment of complicated intra-abdominal infections, skin and soft tissue infections and community-acquired pneumonia.
Fatih Temocin   +8 more
doaj   +2 more sources

Tigecycline susceptibility and the role of efflux pumps in tigecycline resistance in KPC-producing Klebsiella pneumoniae.

open access: yesPLoS ONE, 2015
KPC-producing Klebsiella pneumoniae isolates have emerged as important pathogens of nosocomial infections, and tigecycline is one of the antibiotics recommended for severe infections caused by KPC-producing K. pneumoniae.
Fang He   +6 more
doaj   +2 more sources

The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure [PDF]

open access: yesJournal of Global Antimicrobial Resistance, 2023
: Objectives: We describe the first tigecycline resistant enterococcal isolate in Norway and the mechanisms involved. Material and methods: The Norwegian National Advisory Unit on Detection of Antimicrobial Resistance (K-res).
Kristin Hegstad   +4 more
doaj   +3 more sources

Comparative Genomic Analysis of Tigecycline Resistance Development in Clinical Acinetobacter baumannii Isolates [PDF]

open access: yesInfection and Drug Resistance
Xiaoxia Li,1,* Junnian Liu,2,* Xinyu Zhang,1 Juan Li,3 Luhan Xuan,1 Sue Yuan,1 Jianglin Li,1 Yu Sun,1 Xuefei Du1 1Clinical Laboratory, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People’s Republic of
Li X   +8 more
doaj   +1 more source

Tigecycline [PDF]

open access: yesDrugs, 2005
Tigecycline is the first member of a new class of broad-spectrum antibacterials, the glycylcyclines, that has been specifically developed to overcome the two major mechanisms of tetracycline resistance (ribosomal protection and efflux). In vitro, tigecycline was active against a wide range of Gram-positive and -negative aerobic and anaerobic bacteria ...
James E, Frampton, Monique P, Curran
  +8 more sources

Fitness Costs of Tigecycline Resistance in Acinetobacter baumannii and the Resistance Mechanism Revealed by a Transposon Mutation Library

open access: yesAntibiotics, 2022
Acinetobacter baumannii is one of the main pathogens causing nosocomial and community-acquired infections. Tigecycline is an important antibiotic for the treatment of multidrug-resistant A.
Ping Wang   +5 more
doaj   +1 more source

Genomic and Phenotypic Evolution of Tigecycline-Resistant Acinetobacter baumannii in Critically Ill Patients

open access: yesMicrobiology Spectrum, 2022
Acinetobacter baumannii is an important opportunistic pathogen of nosocomial infections. A. baumannii presently exhibits increasing antibiotic resistance, which poses great challenges to public health. The occurrence of tigecycline-resistant A. baumannii
Jiangang Zhang   +8 more
doaj   +1 more source

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