Frontiers in Microbiology, 2021 Tigecycline has been used as one of the therapeutic choices for the treatment of infections caused by multidrug-resistant Klebsiella pneumoniae. However, the emergence of tigecycline heteroresistance has led to great challenges in treating these ...
Qiaoyu Zhang +3 more
doaj +1 more source
National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]
, 2016 From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L +3 more
core +1 more source
Journal of Global Antimicrobial Resistance, 2020 Objectives: Tigecycline is an antibacterial agent restricted for use against carbapenem-resistant Klebsiella pneumoniae (CRKP). This study aimed to identify the tigecycline resistance mechanism in clinical CRKP isolates obtained from a 60-year-old ...
Yihan Mao +4 more
doaj +1 more source
Prevalence and risk factors of tigecycline-induced liver injury: A multicenter retrospective study
International Journal of Infectious Diseases, 2022 : Objective: We conducted this multicenter retrospective study to evaluate the prevalence, clinical patterns, and risk factors for tigecycline-induced liver injury, which is a type of drug-induced liver injury (DILI).
Zhenwei Yu +5 more
doaj +1 more source
Tigecycline efflux as a mechanism for nonsusceptibility in acinetobacter baumannii [PDF]
, 2007 Tigecycline has an extended spectrum of in vitro antimicrobial activities, including that against multidrug-resistant Acinetobacter. After identifying bloodstream isolates of Acinetobacter with reduced susceptibilities to tigecycline, we performed a ...
Peleg, Anton Y. +2 more
core +1 more source
Antibiotic residues and antibiotic-resistant bacteria in pig slurry used to fertilize agricultural fields [PDF]
, 2020 Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples.
Colson, Lander +9 more
core +2 more sources
Induction of Tigecycline Resistance in Acinetobacter baumannii
Bio-Protocol, 2014 Multidrug resistance Acinetobacter baumannii (A. baumannii) (MDRAB) has emerged as a serious threat in hospitals in recent years. Currently, there are few antibiotics, including tigecycline, available to treat infections caused by MDRAB effectively. Both
Ming-Feng Lin, Yun-You Lin, Chung-Yu Lan
doaj +1 more source
Correlation of ciprofloxacin resistance with the AdeABC efflux system in Acinetobacter baumannii clinical isolates [PDF]
, 2014 Background: Acinetobacter baumannii is one of the most important pathogens capable of colonization in burn patients, leading to drug-resistant wound infections.
Ardebili, A., Lari, A.R., Talebi, M.
core +1 more source
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
Antibiotics, 2020 Tigecycline offers broad anti-bacterial coverage for critically ill patients with complicated infections. A described but less researched side effect is coagulopathy.
Anna Brandtner +9 more
doaj +1 more source