Results 191 to 200 of about 130,672 (308)

Protection of tight junction between RPE cells with tissue factor targeting peptide

, 2018
Xiulan Zou, Guan‐Feng Wang, Dandan Li, Jing-Xia Chen, Chunli Zhang, Yong-Zhen Yu, Wenjie Zhou, Yuping Zou, Benqiang Rao   +8 more
openalex   +1 more source

Effects of cinnamaldehyde and thymol on cytotoxicity, tight junction barrier resistance, and cyclooxygenase-1 and -2 expression in Caco-2 cells [PDF]

, 2017
Heli Putaala, Päivi Nurminen, Kirsti Tiihonen   +2 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Alterations in short-chain fatty acid-associated gut microbiota and tight junction integrity in adolescent major depressive disorder. [PDF]

Transl Psychiatry
Liu X, Geng A, Xia M, Lan J, Wu H, Zhou Z, Huang F, He Y, Lei T, Hur J, Guo K, Yu X, Zhou X.   +12 more
europepmc   +1 more source

Epidermal tight junctions in health and disease [PDF]

, 2014
JM Brandner, Michaela Zorn‐Kruppa, Takeshi Yoshida, Ingrid Moll, L.A. Beck, Anna De Benedetto   +5 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Exploring claudin proteins: from sequence motifs to their impact on tight junction-mediated signaling pathways. [PDF]

Amino Acids
Bao L, Yang S, Zhao W, Zuo Y.
europepmc   +1 more source

Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers [PDF]

, 2010
Nina A. Hering, Jan F. Richter, Susanne M. Krug, Dorothee Günzel, Anja Fromm, Erwin Bohn, Rita Rosenthal, Roland Bücker, Michael Fromm, Hanno Troeger, Jörg D. Schulzke   +10 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren's syndrome. [PDF]

Int J Oral Sci
Mao X, Li H, Min S, Su J, Wei P, Zhang Y, He Q, Wu L, Yu G, Cong X.   +9 more
europepmc   +1 more source