Results 71 to 80 of about 217,887 (317)

Development Of Tilt And Vibration Measurement And Detection System Using MEMS Accelerometer As A Sensor [TK7875. K45 2008 f rb]. [PDF]

, 2008
Dalam projek ini, sistem pengukuran dan pengesan isyarat sudut miring dan isyarat getaran menggunakan meter pecutan MEMS yang mempunyai dua paksi deria X dan Y dibina dengan jayanya. In this project, a measurement and detection system to detect tilt
Abd Wahid, Khairul Anuar
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tilt Measurements in Mechatronic Devices and Mobile Microrobots

Engineering Transactions, 2018
A review of the author’s own research on tilt measurements in mechatronic devices by means of micromachined accelerometers is presented. This comprehensive study addresses such issues as adjusting metrological properties of a tilt sensor for the ...
Sergiusz ŁUCZAK
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Iterated tilted and tilted stably hereditary algebras [PDF]

Colloquium Mathematicum, 2003
The author gives necessary and sufficient conditions for a stably hereditary algebra to be tilted or iterated tilted in terms of its bound quiver. Recall that an algebra \(A\) is `stably hereditary' provided there exists a hereditary algebra \(H\) such that the stable categories \(\underline{\text{mod}}\,A\) and \(\underline{\text{mod}}\,H\) are ...
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Slope Estimation during Normal Walking Using a Shank-Mounted Inertial Sensor

Sensors, 2012
In this paper we propose an approach for the estimation of the slope of the walking surface during normal walking using a body-worn sensor composed of a biaxial accelerometer and a uniaxial gyroscope attached to the shank.
Juan C. Álvarez, Rafael C. González, Diego Álvarez, Antonio M. López   +3 more
doaj   +1 more source

Tilted ECG - An unusual tilt test response

Indian Pacing and Electrophysiology Journal, 2017
Tilt testing is a commonly used diagnostic tool to evaluate syncope of undetermined etiology. We hereby describe a twelve year old male child who developed presyncope during provocative head up tilt testing along with ST segment elevation in cardiac monitor during presyncope.
Gupta, Anunay, Parakh, Neeraj, Juneja, Rajnish   +2 more
openaire   +3 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source