Results 41 to 50 of about 134,958 (300)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Employing FPGA DSP blocks for time-to-digital conversion [PDF]
Metrology and Measurement Systems, 2019 The paper presents a novel implementation of a time-to-digital converter (TDC) in field-programmable gate array (FPGA) devices. The design employs FPGA digital signal processing (DSP) blocks and gives more than two-fold improvement in mean resolution in ...
Paweł Kwiatkowski
doaj +1 more source
Remote Sensing, 2023 Lidar has emerged as an important technology for the high-precision three-dimensional remote sensing of the ocean. While oceanic lidar has been widely deployed on various platforms, its underwater deployment is relatively limited, despite its ...
Zaifa Lin +5 more
doaj +1 more source
Synthesis of time-to-amplitude converter by mean coevolution with adaptive parameters [PDF]
, 2011 Copyright © 2011 the authors and Scientific Research Publishing Inc. This work is licensed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)The challenging task to synthesize automatically a time-
Yerbol A. Sapargaliyev +3 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Time-to-Digital Converter Approach to Physical Attacks on Integrated Circuits
ElectricaShielding is an effective way of protecting the circuitry against physical attacks. Shields are metal structures that cover the top of a circuit. Measuring the delay on these shields allows detection of physical attacks.
Hasan Kaydırma +2 more
doaj +1 more source
Time-to-Digital Converter IP-Core for FPGA at State of the Art
IEEE Access, 2021 The Field Programmable Gate Array (FPGA) structure poses several constraints that make the implementation of complex asynchronous circuits such as Time–Mode (TM) circuits almost unfeasible.
Fabio Garzetti +3 more
doaj +1 more source
Variation Resilient Adaptive Controller for Subthreshold Circuits
, 2009 Subthreshold logic is showing good promise as a viable ultra-low-power circuit design technique for power-limited applications. For this design technique to gain widespread adoption, one of the most pressing concerns is how to improve the robustness of ...
B. Mishra +5 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source