Results 41 to 50 of about 30,124 (283)

Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1‐phosphate in extravillous trophoblasts

Reproductive Medicine and Biology, 2021
Purpose Extracellular matrix remodeling is essential for extravillous trophoblast (EVT) cell migration and invasion during placental development and regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs ...
Kirti R. Chahar, Vijay Kumar, Phulwanti K. Sharma, Daniela Brünnert, Vibha Kaushik, Pragya Gehlot, Indu Shekhawat, Suman Kumar, Ajay Kumar Sharma, Sandhya Kumari, Pankaj Goyal   +10 more
doaj   +1 more source

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Echinoderms: Structure and Possible Functions

Cells, 2021
Echinoderms are one of the most ancient groups of invertebrates. The study of their genomes has made it possible to conclude that these animals have a wide variety of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs ...
Igor Yu. Dolmatov, Vladimir A. Nizhnichenko, Lyudmila S. Dolmatova   +2 more
doaj   +1 more source

TIMPs Expression as A Maternal Cell Free Plasma Biomarker of Severe Preeclampsia: A Case-Control Study [PDF]

Cell Journal, 2023
Objective: Preeclampsia (PE) is a pregnancy related disorder with prevalence of 6-7%. Insufficient trophoblasticinvasion leads to incomplete remodeling of spiral arteries and consequent decrease in feto-placental perfusion. Alteredplacental expression of
Sara Seydabadi, Habib Nikukar, Fahimeh Ghotbizadeh Vahdani, Fariba Ramezanali, Maryam Shahhoseini, Raha Favaedi, Azadeh Ghaheri, Elham Etesami, Mohammadreza Zamanian   +8 more
doaj   +1 more source

Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke. [PDF]

, 2016
Numerous studies have documented increases in matrix metalloproteinases (MMPs), specifically MMP-9 levels following stroke, with such perturbations associated with disruption of the blood brain barrier (BBB), increased risk of hemorrhagic complications ...
Adibhatla, Agrawal, Alcaide, Amantea, Amantea, Anthony, Asahi, Asahi, Asahi, Bajor, Bakowski, Bauer, Benarroch, Burk, Candelario-Jalil, Carbone, Castellanos, Castellanos, Chang, Chesler, Choi, Clark, Clark, Conant, Copin, Cuadrado, Cuadrado, Cunningham, Dejonckheere, Fanjul-Fernández, Fernandez-Patron, Ferry, Fiorelli, Frank R. Sharp, Fujimoto, Fujimura, Fujimura, Gasche, Gasche, Gasche, Gautier, Gidday, Golab, Gu, Gurney, Gürsoy-Ozdemir, Hacke, Harris, Heo, Heo, Horstmann, Hu, Inzitari, Jickling, Justicia, Keck, Kelly, Khandoga, Kim, Kuroiwa, Kurzepa, Lapchak, Lee, Lenglet, Lenglet, Li, Lucivero, Lukes, Lynch, Machado, Maier, Manabe, McCarthy, Moldes, Montaner, Montaner, Montaner, Montaner, Montaner, Montaner, Mun-Bryce, Murata, Nguyen, Ning, Oda, Opdenakker, Orbe, Piccardi, Planas, Ra, Ramos-Fernandez, Ranasinghe, Renée J. Turner, Reynolds, Rivera, Rodrigues, Rodríguez, Rodríguez-Yáñez, Romanic, Rosell, Rosell, Rosell, Rosenberg, Rosenberg, Rosenberg, Rosenberg, Sandoval, Schnoor, Shigemori, Si-Tayeb, Sotgiu, Steadman, Sternlicht, Sumii, Svedin, Tan, Tang, Tsuji, Tsuruoka, Turba, Van den Steen, Vandooren, Vukasovic, Wang, Wang, Wang, Yan, Yang, Yang, Yushchenko, Zhao, Zhao, Zhao, Zozulya   +133 more
core   +3 more sources

Abnormalities in soluble CD147 / MMPs / TIMPs axis in Ankylosing Spondylitis patients with and without a history of Acute Anterior Uveitis / Anomalii ale axei CD147 solubil / MMPs / TIMPs la pacienții cu spondilită anchilozantă cu sau fără uveită acută anterioară

Romanian Journal of Laboratory Medicine, 2014
Spondilita Anchilozantă (SA) este prototipul formei axiale a spondiloartritelor. În pofida studiilor extinse, sunt încă incomplet înțelese mecansimele complexe legate de procesele celulare și moleculare anormale din SA.
Mitulescu Traian Costin, Voinea Liliana Mary, Predeteanu Denisa, Banica Leontina Mirela, Stavaru Crina, Matache Cristiana   +5 more
doaj   +1 more source

Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells

Current Issues in Molecular Biology, 2021
Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4).
Yoji Hisamatsu, Hiromi Murata, Hiroaki Tsubokura, Yoshiko Hashimoto, Masaaki Kitada, Susumu Tanaka, Hidetaka Okada   +6 more
doaj   +1 more source

Do Matrix Metalloproteases and Tissue Inhibitors of Metalloproteases in Tenocytes of the Rotator Cuff Differ with Varying Donor Characteristics? [PDF]

, 2015
An imbalance between matrix metalloproteases (MMPs) and the tissue inhibitors of metalloproteases (TIMPs) may have a negative impact on the healing of rotator cuff tears.
Aleyt, Thomas, Geißler, Sven, Gerhardt, Christian, Klatte-Schulz, Franka, Pauly, Stephan, Scheibel, Markus, Wildemann, Britt   +6 more
core   +2 more sources

Higher levels of circulating TIMP-4 in preeclampsia is strongly associated with clinical parameters and microRNA

Clinical and Experimental Hypertension, 2018
Background: Preeclampsia results in maternal and fetal complications and some studies have reported the role of MMPs and TIMPs in its pathophysiology.
Valéria C. Sandrim, Solange Diniz, Nibia Mariana Eleuterio, Karina B. Gomes, Luci Maria S. Dusse, Ricardo C. Cavalli   +5 more
doaj   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong, Rahman, Irfan, Sun, Jun, Sundar, Isaac K, Wu, Shaoping   +4 more
core   +1 more source

Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis? [PDF]

, 2017
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is characterized by a peculiar mechanism of action. In fact, S1P, which is produced inside the cell, can act as an intracellular mediator, whereas after its export outside the cell, it can act as ...
Frati, Alessia, Meacci, Elisabetta, Monaco, Lucia, Pierucci, Federica, Vestri, Ambra   +4 more
core   +2 more sources