Results 21 to 30 of about 16,067 (252)
Promoting uptake and integration of climate smart agriculture technologies, innovations and management practices into policy and practice in Nigeria [PDF]
International Journal of Climate Change Strategies and Management, 2022 Purpose – This study aims to explore possible ways to promote uptake and integration of climate-smart agriculture (CSA)-Technologies, Innovations and Management Practices (TIMPS) into policy and practice in Nigeria through the development of actionable ...
Chinwoke Clara Ifeanyi-Obi +5 more
doaj +1 more source
The in vitro activity of ADAM‐10 is inhibited by TIMP‐1 and TIMP‐3 [PDF]
FEBS Letters, 2000 A recombinant soluble form of the catalytic domain of human ADAM‐10 was expressed as an Fc fusion protein from myeloma cells. The ADAM‐10 was catalytically active, cleaving myelin basic protein and peptides based on the previously described ‘metallosheddase’ cleavage sites of tumour necrosis factor α, CD40 ligand and amyloid precursor protein.
Amour, Augustin +7 more
openaire +2 more sources
Microbial Cell Factories, 2017 Background As regulators of multifunctional metalloproteinases including MMP, ADAM and ADAMTS families, tissue inhibitors of metalloproteinases (TIMPs) play a pivotal role in extracellular matrix remodeling, which is involved in a wide variety of ...
Ki Baek Lee +5 more
doaj +1 more source
Whole organism profiling of the Timp gene family
Matrix Biology Plus, 2023 Tissue inhibitor of metalloproteinases (TIMPs/Timps) are an endogenous family of widely expressed matrisome-associated proteins that were initially identified as inhibitors of matrix metalloproteinase activity (Metzincin family proteases).
David Peeney +8 more
doaj +1 more source
Reproductive Medicine and Biology, 2021 Purpose Extracellular matrix remodeling is essential for extravillous trophoblast (EVT) cell migration and invasion during placental development and regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs ...
Kirti R. Chahar +10 more
doaj +1 more source
Cells, 2021 Echinoderms are one of the most ancient groups of invertebrates. The study of their genomes has made it possible to conclude that these animals have a wide variety of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs ...
Igor Yu. Dolmatov +2 more
doaj +1 more source
TIMPs Expression as A Maternal Cell Free Plasma Biomarker of Severe Preeclampsia: A Case-Control Study [PDF]
Cell Journal, 2023 Objective: Preeclampsia (PE) is a pregnancy related disorder with prevalence of 6-7%. Insufficient trophoblasticinvasion leads to incomplete remodeling of spiral arteries and consequent decrease in feto-placental perfusion. Alteredplacental expression of
Sara Seydabadi +8 more
doaj +1 more source
MMP–TIMP interaction depends on residue 2 in TIMP‐4
FEBS Letters, 2001 Extracellular matrix remodeling and degradation are of great importance in both physiological and pathological situations. Matrix metalloproteinases (MMPs) and their natural occurring inhibitors – tissue inhibitors of metalloproteinases (TIMPs) – are involved in matrix turnover. Among the TIMPs there is only little specificity for inhibiting individual
Stratmann, B, Farr, M, Tschesche, Harald
openaire +3 more sources
Romanian Journal of Laboratory Medicine, 2014 Spondilita Anchilozantă (SA) este prototipul formei axiale a spondiloartritelor. În pofida studiilor extinse, sunt încă incomplet înțelese mecansimele complexe legate de procesele celulare și moleculare anormale din SA.
Mitulescu Traian Costin +5 more
doaj +1 more source
Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells
Current Issues in Molecular Biology, 2021 Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4).
Yoji Hisamatsu +6 more
doaj +1 more source