The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review) [PDF]
, 2011 BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease ...
Aaron +32 more
core +1 more source
Pharmaceutics, 2020 The effects of tiotropium bromide soft mist inhalers (SMIs) in patients with chronic obstructive pulmonary disease (COPD) receiving mechanical ventilation remain unexplored.
Pin-Kuei Fu +7 more
doaj +1 more source
New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma [PDF]
, 2017 Introduction: Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma.
Thomson, Neil C.
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New possibilities for asthma therapy in children
Медицинский совет, 2018 This article discusses issues of clinical diagnosis and course of bronchial asthma in children. We discuss assessment of asthma severity and, accordingly, the extent of the step-by-step therapy according to updated recommendations (GINA 2018). Particular
T. N. Surovenko, Е. F. Glushkova
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Therapy and control of bronchial asthma in children and adolescents
Медицинский совет, 2020 Up to 22% of the population in the world suffer from bronchial asthma according to the data from different regions and sources. This is about 358 million people.
T. N. Surovenko, E. F. Glushkova
doaj +1 more source
Comorbidities of patients in tiotropium clinical trials : comparison with observational studies of patients with chronic obstructive pulmonary disease [PDF]
, 2015 Acknowledgments The authors are fully responsible for all content and editorial decisions made, were involved at all stages of manuscript development, and have approved the final version for publication.
Celli, Bartolome +5 more
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Van-e cardiovascularis mellékhatásuk az inhalációs antikolinerg szereknek? [PDF]
, 2015 Absztrakt Az összefoglaló célja az inhalációs antikolinerg szerek cardiovascularis veszélyének tárgyalása krónikus obstruktív tüdőbetegségben.
Nagy, László Béla
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Comparative efficacy of long-acting bronchodilators for COPD - a network meta-analysis [PDF]
, 2013 Background: Clinicians are faced with an increasingly difficult choice regarding the optimal bronchodilator for patients with chronic obstructive pulmonary disease (COPD) given the number of new treatments. The objective of this study is to evaluate the
Baldwin, M +8 more
core +3 more sources
Inhaled tiotropium bromide and risk of stroke [PDF]
British Journal of Clinical Pharmacology, 2009 WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Conflicting studies have raised uncertainty over the vascular effects of the long‐acting anticholinergic, tiotropium bromide. WHAT THIS STUDY ADDS • Our results show no increased risk of stroke with tiotropium bromide, or with inhaled anticholinergics in general.AIMSA recent communication from the United ...
Anthony, Grosso +5 more
openaire +2 more sources
Spirocyclic Diamine Scaffolds for Medicinal Chemistry
Helvetica Chimica Acta, Volume 109, Issue 1, January 2026.Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel +3 more
wiley +1 more source