The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov+5 more
doaj +1 more source
Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype [PDF]
To the Editor: Although currently available asthma medications are very effective in the majority of cases, there remains a subgroup for which disease control is difficult. Anticholinergics have long been used to treat asthma, although their current role in therapy is supplementary 1.
Yoshinori Haruta+6 more
openaire +3 more sources
A study to assess COPD Symptom-based Management and to Optimise treatment Strategy in Japan (COSMOS-J) based on GOLD 2011 [PDF]
Background and objective: The Global initiative for chronic Obstructive Lung Disease(GOLD) Committee has proposed a chronic obstructive pulmonary disease (COPD) assessment framework focused on symptoms and on exacerbation risk. This study will evaluate a
Betsuyaku, T+7 more
core +1 more source
A New Monomeric Interpretation of Intrinsic Optical Bistability Observed in Yb3+ - Doped Bromide Materials [PDF]
We present a mechanism able to show intrinsic bistable behaviour involving single Yb3+ ions embedded into bromide lattices, in which intrinsic optical bistability (IOB) has been observed. The mechanism is based on the experimentally found coupling between the Yb3+ ion and the totally symmetric local mode of vibration of the [YbBr6]3- coordination unit.
arxiv +1 more source
Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease (Review) [PDF]
Background The long-acting bronchodilator tiotropium and single inhaler combination therapy of inhaled corticosteroids and long-acting beta(2)-agonists are both commonly used for maintenance treatment of chronic obstructive pulmonary disease.
Appleton+10 more
core +1 more source
UV photodissociation of methyl bromide and methyl bromide cation studied by velocity map imaging [PDF]
We employ the velocity map imaging technique to measure kinetic energy and angular distributions of state selected CH3 (v2=0,1,2,3) and Br (2P3/2,2P1/2) photofragments produced by methyl bromide photolysis at 215.9 nm. These results show unambiguously that the Br and Br* forming channels result in different vibrational excitation of the umbrella mode ...
arxiv +1 more source
Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. [PDF]
BACKGROUND: Pharmacological therapy for chronic obstructive pulmonary disease (COPD) is aimed at relieving symptoms, improving quality of life and preventing or treating exacerbations.Treatment tends to begin with one inhaler, and additional therapies ...
Aalbers+511 more
core +1 more source
Compatibilization of HDPE/agar biocomposites with eutectic-based ionic liquid containing surfactant [PDF]
In this research, eutectic-based ionic liquid specifically choline chloride/glycerol was prepared at a 1:2 mole ratio. The choline chloride/glycerol was added with the different content of surfactant (hexadecyltrimethylammonium bromide). The choline chloride/glycerol-hexadecyltrimethylammonium bromide was introduced into high-density polyethylene/agar ...
arxiv +1 more source
Composition, Size, and Surface Functionalization dependent Optical Properties of Lead Bromide Perovskite Nanocrystals [PDF]
The photoluminescence (PL), color purity, and stability of lead halide perovskite nanocrystals depend critically on the surface passivation. We present a study on the temperature dependent PL and PL decay dynamics of lead bromide perovskite nanocrystals characterized by different types of A cations, surface ligands, and nanocrystal sizes.
arxiv +1 more source
Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD [PDF]
Date of Aceptance: 12/02/2015 Acknowledgments The authors were assisted in the preparation of the manuscript by Sarah Filcek, a professional medical writer at CircleScience (Tytherington, UK), part of KnowledgePoint360, an Ashfield Company.
Beeh, Kai M+3 more
core +1 more source