Results 51 to 60 of about 4,977 (213)

PRS45 Cost Effectiveness of Umeclidinium/Vilanterol (UMEC/VI) Combination Therapy Among Symptomatic COPD Patients [PDF]

, 2011
Fitxes dels ...
Punekar, Y.S., Roberts, G., Ismaila, A., O'Leary, M.   +3 more
core   +1 more source

Deprescribing drugs with anticholinergic effects in older patients with increased risk of dementia in the multicomponent intervention study AgeWell.de

British Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3489-3500, December 2025.
Aim Drugs with anticholinergic effects are often considered as potentially inappropriate medications, especially for older patients, and deprescribing such drugs may improve cognitive function. The aim was to investigate the effectiveness of counselling on drug risks as part of a multimodal intervention to prevent cognitive decline. Methods The AgeWell.
Laura K. Lepenies, Hanna M. Seidling, Alexander Pabst, Melanie Luppa, Juliane Döhring, Martin Williamson, Thomas Frese, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans‐Helmut König, Jochen René Thyrian, Birgitt Wiese, Steffi G. Riedel‐Heller, David Czock   +14 more
wiley   +1 more source

Tiotropium in chronic obstructive pulmonary disease – a review of clinical development

Respiratory Research, 2020
Background Bronchodilators are the mainstay of pharmacological treatment in chronic obstructive pulmonary disease (COPD), and long-acting muscarinic antagonist (LAMA) monotherapy is recommended as initial treatment for Global Initiative for Chronic ...
Antonio Anzueto, Marc Miravitlles
doaj   +1 more source

Diagnosis and Pharmacotherapy of Stable Chronic Obstructive Pulmonary Disease : The Finnish Guidelines [PDF]

, 2015
Peer ...
Anthonisen NR, Appleton S, Appleton S, Appleton S, Barr RG, Cates CJ, Chong J, Chronic Obstructive Pulmonary Disease (online), Donohue JF, Haahtela T, Harju T, Harju T, Hay JG, Higgings BG, Kankaanranta H, Kankaanranta H, Kankaanranta H, Karner C, Karner C, Karner C, Kew KM, Kew KM, Lehtimäki L, Mohamed Hoesein FA, Nannini LJ, Nannini LJ, Nannini LJ, Nannini LJ, Poole P, Poole PJ, Ram FS, Sestini P, Tobacco Dependence and Cessation (online), Walters JA, Yang IA   +34 more
core   +2 more sources

Taste and Smell Disorders in Children and Young Adults With Cystic Fibrosis and Primary Ciliary Dyskinesia—A Prospective Comparative Study

Pediatric Pulmonology, Volume 60, Issue 12, December 2025.
ABSTRACT Background In cystic fibrosis (CF), the defect of the CF transmembrane conductance regulator (CFTR) can also affect sensory nerve cell function, as recently demonstrated in animal models. The aim of this prospective cohort study was to investigate whether taste and smell disorders in CF correlate with persistent CFTR dysfunction detectable by ...
Lea Christiane Beermann, Lisa Sophie Demski, Lynn Eitner, Stefanie Dillenhöfer, Anne Schlegtendal, Claire Mallon, Folke Brinkmann, Christoph Maier, Thomas Lücke, Anna Teresa Hoffmann   +9 more
wiley   +1 more source

Tiotropium: a new therapeutic option in asthma

Monaldi Archives for Chest Disease, 2013
Tiotropium: a new therapeutic option in asthma. F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro. Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic ...
F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro   +6 more
doaj   +1 more source

Acetylcholine-treated murine dendritic cells promote inflammatory lung injury [PDF]

, 2019
In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Alcain, Julieta María, Candolfi, Marianela, Geffner, Jorge Raúl, Gori, María Soledad, Jancic, Carolina Cristina, Moreno Ayala, Mariela Alejandra, Salamone, Gabriela Veronica, Vanzulli, Silvia, Vermeulen, Elba Monica   +8 more
core   +1 more source

Isolated Unilateral Pleural Effusion Associated With Hypothyroidism: A Case Report and Review of the Literature

Respirology Case Reports, Volume 13, Issue 11, November 2025.
Hypothyroidism rarely causes isolated pleural effusion, as such effusions are typically associated with comorbidities like heart failure or malignancy. This report presents a case of borderline transudative pleural effusion attributed solely to hypothyroidism after thorough differential diagnosis. Hypothyroidism should be considered in the differential
Hesam Amini, Fereshteh Attaran, Sara Soltanmohammadi   +2 more
wiley   +1 more source

Dual bronchodilation in COPD : lung function and patient-reported outcomes – a review [PDF]

, 2016
Peer reviewedPublisher ...
Ostrem, Anders, Price, David, Thomas, Mike, Welte, Tobias   +3 more
core   +2 more sources

Efficacy of Dupilumab in a Woman With Severe Asthma Complicated by Eosinophilic Sinusitis and a Desire to Have a Baby: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Since 2008, the patient had been undergoing asthma treatment, but it was poorly controlled. She also had comorbid conditions including eosinophilic sinusitis, allergic rhinitis, conjunctivitis, and a non‐functional adrenal tumor. After marriage in 2018 (age 34 years), her asthma control remained poor, and she was unable to conceive spontaneously ...
Akari Neoi, Masakiyo Yatomi, Yurino Nagata, Daisuke Higeta, Daisuke Shimizu, Karin Kuno, Yuri Sawada, Mari Sato, Haruka Aoki‐Saito, Koichi Yamaguchi, Hiroaki Tsurumaki, Yosuke Miura, Kenichiro Hara, Noriaki Sunaga, Yasuhiko Koga, Kazuaki Chikamatsu, Takeshi Hisada, Toshitaka Maeno   +17 more
wiley   +1 more source