Results 41 to 50 of about 210,372 (257)
Current microfluidic platforms for reverse engineering of cornea
Materials Today Bio, 2023 According to the World Health Organization, corneal blindness constitutes 5.1% of global blindness population. Surgical outcomes have been improved significantly in the treatment of corneal blindness. However, corneal transplantation is limited by global
Qinyu Li +7 more
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Novel Strategies in Artificial Organ Development: What Is the Future of Medicine?
Micromachines, 2020 The technology of tissue engineering is a rapidly evolving interdisciplinary field of science that elevates cell-based research from 2D cultures through organoids to whole bionic organs. 3D bioprinting and organ-on-a-chip approaches through generation of
Marta Klak +9 more
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Frontiers in Bioengineering and Biotechnology, 2022 Organ-on-a-chip (OOC) is a new type of biochip technology. Various types of OOC systems have been developed rapidly in the past decade and found important applications in drug screening and precision medicine.
Wanying Gao +8 more
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Proteomic Classification of Pancreatic Adenocarcinoma Tissue Using Protein Chip Technology
Gastroenterology, 2006 Pancreatic adenocarcinoma is a most devastating cancer that presents late and is rapidly progressive. This study aimed to identify unique, tissue-specific protein biomarkers capable of differentiating pancreatic adenocarcinoma (PC) from adjacent uninvolved pancreatic tissue (AP), benign pancreatic disease (B), and nonmalignant tumor tissue (NM).Tissue ...
Scarlett, Christopher +6 more
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Tissue Culture On-chip Design using Multivariable Molecular Network
Procedia Engineering, 2012 AbstractThis paper proposed tissue culture on-chip design using multivariable molecular network by using three network combinations such as star, bus and ring networks. A chip consists of star networks that allow the trapping molecule (nutrient or gene) circulation within design a circuit.
Authasing, S. +3 more
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Melanoma-on-a-chip model for anticancer drug injecting delivery method
SLAS TechnologyThe pharmaceutical and cosmetic industries are encountering a challenge in adopting new study models for product development. there has been a growing interest in organ-on-a-chip systems, and particularly for generating skin models.
Pedro Herreros +3 more
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Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery
Frontiers in Pharmacology, 2020 Organoids are adept at preserving the inherent complexity of a given cellular environment and when integrated with engineered micro-physiological systems (MPS) present distinct advantages for simulating a precisely controlled geometrical, physical, and ...
Jing Bai, Chunming Wang
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Enhanced tenogenic differentiation and tendon-like tissue formation by CHIP overexpression in tendon-derived stem cells [PDF]
Acta Biochimica et Biophysica Sinica, 2017 The carboxyl terminus of Hsc70-interacting protein (CHIP, also known as STUB1) plays critical roles in the proliferation and differentiation of many types of cells. The potential function of CHIP in tendon-derived stem cells (TDSCs) remains largely unknown at present.
Weifeng, Han +3 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source