Results 31 to 40 of about 210,372 (257)

Human Microphysiological Models of Intestinal Tissue and Gut Microbiome

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The gastrointestinal (GI) tract is a complex system responsible for nutrient absorption, digestion, secretion, and elimination of waste products that also hosts immune surveillance, the intestinal microbiome, and interfaces with the nervous system ...
Steven N. Steinway   +5 more
doaj   +1 more source

Designing Biomaterial Platforms for Cardiac Tissue and Disease Modeling

open access: yesAdvanced NanoBiomed Research, 2021
Heart disease is one of the leading causes of death in the world. There is a growing demand for in vitro cardiac models that can recapitulate the complex physiology of the cardiac tissue.
Andrew House   +3 more
doaj   +1 more source

Reports on the sensitivity enhancement in interferometric based biosensors by biotin-streptavidin system

open access: yesHeliyon, 2023
Antibody biotinylation is a process of attaching biotin molecules to antibodies by chemically modifying specific functional groups on the antibodies without altering their antigen recognition specificity.
A.M.M. Murillo, M. Holgado, M. Laguna
doaj   +1 more source

Cutting-Edge Technologies for Inflamed Joints on Chip: How Close Are We?

open access: yesFrontiers in Immunology, 2022
Osteoarthritis (OA) is a painful and disabling musculoskeletal disorder, with a large impact on the global population, resulting in several limitations on daily activities.
Emine Kahraman   +8 more
doaj   +1 more source

Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device [PDF]

open access: yesLab on a Chip, 2021
A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.
Kazuki Yamamoto   +8 more
openaire   +2 more sources

Shape-defined solid micro-objects from poly(d,l-lactic acid) as cell-supportive counterparts in bottom-up tissue engineering

open access: yesMaterials Today Bio, 2019
In bottom-up tissue engineering, small modular units of cells and biomaterials are assembled toward ​larger and more complex ones. In conjunction with a new implementation of this approach, a novel method to fabricate microscale objects from biopolymers ...
A.M. Leferink   +7 more
doaj   +1 more source

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

open access: yesSensors, 2015
Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate ...
Ana Rubina Perestrelo   +3 more
doaj   +1 more source

Engineering the Cellular Microenvironment of Post-infarct Myocardium on a Chip

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial infarctions are one of the most common forms of cardiac injury and death worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium, which is followed by a repair process with inflammatory, proliferative, and ...
Natalie N. Khalil   +2 more
doaj   +1 more source

Advances in Engineering Human Tissue Models

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions.
Chrysanthi-Maria Moysidou   +2 more
doaj   +1 more source

Analysis of inflammatory biomarkers from tissue biopsies by chip‐based immunoaffinity CE [PDF]

open access: yesELECTROPHORESIS, 2007
AbstractTo aid in the biochemical analysis of human skin biopsies, a semiautomatic chip‐based CE system has been developed for measuring inflammatory biomarkers in microdissected areas of the biopsy. Following solubilization of the dissected tissue, the desired biomarkers were isolated by immunoaffinity capture using a panel of 12 antibodies ...
Terry M, Phillips, Edward F, Wellner
openaire   +2 more sources

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