Results 21 to 30 of about 210,372 (257)
Tissue Nanotransfection Silicon Chip and Related Electroporation-Based Technologies for In Vivo Tissue Reprogramming. [PDF]
Nanomaterials (Basel)Tissue nanotransfection (TNT), a cutting-edge technique of in vivo gene therapy, has gained substantial attention in various applications ranging from in vivo tissue reprogramming in regenerative medicine, and wound healing to cancer treatment. This technique harnesses the advancements in the semiconductor processes, facilitating the integration of ...
Xuan Y, Wang C, Ghatak S, Sen CK.
europepmc +4 more sources
Biomimetic tissues on a chip for drug discovery [PDF]
Drug Discovery Today, 2012 Developing biologically relevant models of human tissues and organs is an important enabling step for disease modeling and drug discovery. Recent advances in tissue engineering, biomaterials and microfluidics have led to the development of microscale functional units of such models also referred to as 'organs on a chip'.
Amir M, Ghaemmaghami +4 more
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A tissue impedance measurement chip for myocardial ischemia detection [PDF]
IEEE Transactions on Circuits and Systems I: Regular Papers, 2005 In this paper, the design of a specific integrated circuit for the measurement of tissue impedances is presented. The circuit will be part of a multi-micro-sensor system intended to be used in cardiac surgery for sensing biomedical parameters in living bodies. Myocardium tissue impedance is one of these parameters which allows ischemia detection.
Alberto Yufera +5 more
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Integrating mechanical sensor readouts into organ-on-a-chip platforms
Frontiers in Bioengineering and Biotechnology, 2022 Organs-on-a-chip have emerged as next-generation tissue engineered models to accurately capture realistic human tissue behaviour, thereby addressing many of the challenges associated with using animal models in research.
Ingrid Anaya Morales +5 more
doaj +1 more source
Conventional and Recent Trends of Scaffolds Fabrication: A Superior Mode for Tissue Engineering
Pharmaceutics, 2022 Tissue regeneration is an auto-healing mechanism, initiating immediately following tissue damage to restore normal tissue structure and function.
Islam M. Adel +2 more
doaj +1 more source
New Endeavors of (Micro)Tissue Engineering: Cells Tissues Organs on-Chip and Communication Thereof [PDF]
Cells Tissues Organs, 2021 The development of new therapies is tremendously hampered by the insufficient availability of human model systems suitable for preclinical research on disease target identification, drug efficacy, and toxicity. Thus, drug failures in clinical trials are too common and too costly.
Haysam M.M.A.M. Ahmed +1 more
openaire +2 more sources
Biosensors, 2022 The gingival epithelium–capillary interface is a unique feature of periodontal soft tissue, preserving periodontal tissue homeostasis and preventing microorganism and toxic substances from entering the subepithelial tissue.
Laidi Jin +9 more
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A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip (OOAC) Systems
Bioengineering, 2021 Drug and chemical development along with safety tests rely on the use of numerous clinical models. This is a lengthy process where animal testing is used as a standard for pre-clinical trials.
Luana A. Osório +2 more
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Recent advancements and future requirements in vascularization of cortical organoids
Frontiers in Bioengineering and Biotechnology, 2022 The fields of tissue engineering and disease modeling have become increasingly cognizant of the need to create complex and mature structures in vitro to adequately mimic the in vivo niche.
Erin LaMontagne +5 more
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Inkjet-based bioprinting for tissue engineering [PDF]
Organoid, 2023 Inkjet bioprinting, a derivative of traditional inkjet technology, is gaining recognition in the fields of life sciences and tissue engineering due to its ability to produce picoliter volume droplets at high speeds in a non-contact fashion.
Ju An Park, Yunji Lee, Sungjune Jung
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