Results 21 to 30 of about 70,024 (278)
Immunological pathogenesis of inflammatory bowel disease: focus on tissue resident memory T cells. [PDF]
Front ImmunolTissue-resident memory T (TRM) cells are a type of tissue-restricted memory T cells with terminal differentiation and a memory function. They exist in mucosal tissues for a long period. In the absence of disease, TRM cells promote essential inflammation,
Hu J +11 more
europepmc +2 more sources
LOCAL IMMUNITY BY TISSUE-RESIDENT CD8+ MEMORY T CELLS [PDF]
Frontiers in Immunology, 2012 Microbial infection primes a CD8+ cytotoxic T cell response that gives rise to a long-lived population of circulating memory cells able to provide protection against systemic reinfection.
Thomas eGebhardt, Laura K Mackay
doaj +4 more sources
Editorial: Tissue Resident Memory T Cells
Frontiers in Immunology, 2019 Fathia Mami-Chouaib +2 more
doaj +3 more sources
Tissue‐Resident Memory T Cells: Pioneering New Avenues in Cancer Immunotherapy [PDF]
Cancer MedicineBackground Tissue‐resident memory T cells (TRM) are a specialized subset of memory T cells that reside in nonlymphoid tissues and draining lymph nodes, playing a critical role in immune surveillance and tumor immunity.
Yao Xiao, Qi‐Chao Yang, Zhi‐Jun Sun
doaj +2 more sources
Spatial organization of tissue-resident memory T cells.
ImmunityTissue-resident memory T (TRM) cells durably reside in peripheral tissues, poised to deliver rapid local immune protection. TRM cells are found in most organs, and they are a core component of immunological memory, complementing circulating memory T cell
Thomas N. Burn, Laura K. Mackay
semanticscholar +3 more sources
Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells [PDF]
Frontiers in Immunology, 2018 Tissue-resident memory T cells (TRM) persist in peripheral tissues for long periods of time in the absence of antigenic stimulation. Upon re-encounter with cognate antigen, TRM trigger an immediate immune response at the local tissue microenvironment and
Youdong Pan, Thomas S. Kupper
doaj +3 more sources
Induction of tissue resident memory T cells by measles vaccine vector [PDF]
Human Vaccines & ImmunotherapeuticsMeasles live attenuated vaccine (MV) induces strong humoral and cellular systemic memory responses allowing the successful control of measles since decades.
Heidy Vera-Peralta +8 more
doaj +2 more sources
Regulation of tissue-resident memory T cells by the Microbiota [PDF]
Mucosal Immunology, 2022 Resident memory T cells (Trms) predominantly reside within tissue and are critical for providing rapid protection against invasive viruses, fungi and bacteria. Given that tissues are heavily impacted and shaped by the microbiota, it stands to reason that Trms are also influenced by the microbiota that inhabits barrier sites.
Abigail E. Overacre-Delgoffe +1 more
openaire +2 more sources
Heterogeneity of tissue resident memory T cells
Immunology Letters, 2022 Non-lymphoid organs, in mice and humans, contain CD8+ tissue-resident memory T (TRM) cells. They play important roles in tissue homoeostasis as well as defence against infections and cancer. TRM cells have common characteristics that enables their tissue residency and function.
Špela Konjar +3 more
openaire +2 more sources
Frontiers in Immunology, 2021 CD8 positive, tissue resident memory T cells (TRM) are a specialized subset of CD8 memory T cells that surveil tissues and provide critical first-line protection against tumors and pathogen re-infection.
Curtis J. Pritzl +2 more
doaj +1 more source