Results 91 to 100 of about 3,935,952 (212)

Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]

, 2015
Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine, Beattie, Wendy, Brown, Catriona E., Carty, David M., Delles, Christian, Forrest, Rachel, Freeman, Dilys J., McBride, Martin W., McClure, John D., Robinson, Scott W., Sharafetdinova, Liliia, Small, Heather, Work, Lorraine M.   +12 more
core   +1 more source

Tissue Factor and Atherothrombosis

Current Pharmaceutical Design, 2015
Tissue factor (TF) is known to be the key element in the initiation of the extrinsic pathway of the coagulation cascade and appears to be a critical determinant of atherosclerotic plaque thrombogenicity. TF is needed to produce thrombin from prothrombin. In the extrinsic pathway, TF activates factor Vll. TF is expressed mainly on subendothelial tissues,
D, Saha, Saha, S, E G, Sergeeva, Z I, Ionova, A V, Gorbach   +4 more
openaire   +5 more sources

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

A multiscale model for collagen alignment in wound healing [PDF]

, 2005
It is thought that collagen alignment plays a significant part in scar tissue formation during dermal wound healing. We present a multiscale model for collagen deposition and alignment during this process. We consider fibroblasts as discrete units moving
Dallon, J. C., Maini, P. K., Sherratt, J. A.   +2 more
core   +1 more source

Disseminated intravascular coagulation

Indian Journal of Anaesthesia, 2014
Disseminated intravascular coagulation (DIC) is a reflection of an underlying systemic disorder which affects the coagulation system, simultaneously resulting in pro-coagulant activation, fibrinolytic activation, and consumption coagulopathy and finally ...
A Venugopal
doaj   +1 more source

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]

, 2014
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin, Cho, Kae Won, Cozacov, Zoharit, Hu, Chun-Rui, Li, Siming, Lin, Jiandie D, Lumeng, Carey N, Saltiel, Alan R, Uhm, Maeran, Wang, Guo-Xiao, Xu, Acer E   +10 more
core   +2 more sources

Characterization of physical properties of tissue factor–containing microvesicles and a comparison of ultracentrifuge-based recovery procedures

Journal of Extracellular Vesicles, 2014
Microvesicles were isolated from the conditioned media of 3 cell lines (MDA-MB-231, AsPC-1 and A375) by ultracentrifugation at a range of relative centrifugal forces, and the tissue factor (TF) protein and activity, microvesicle number, size distribution
Camille Ettelaie, Mary E. W. Collier, Anthony Maraveyas, Rammile Ettelaie   +3 more
doaj   +1 more source

The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity [PDF]

, 2015
Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells.
Agathocleous, Alcedo, Aza-Blanc, Bai, Bellavia, Boyman, Brennan, Buckland, Chan, Cheng, Crompton, D'Acquisto, de la Roche, Decker, Dennler, Drakopoulou, El Andaloussi, Feske, Finetti, Furler, Furmanski, Furmanski, Gilmour, Hafezi-Moghadam, Hager-Theodorides, Hager-Theodorides, Hatayama, Huang, Hui, Huse, Ingham, Jiang, Kahn, Kasper, Kim, Kumabe, Lau, Le, Lee, Li, Lowrey, Marigo, Matise, Medyouf, Michel, Mo, Neumann, Nielsen, Outram, Park, Perry, Pola, Priatel, Priatel, Reynolds, Riobó, Rohatgi, Rowbotham, Rowbotham, Rowbotham, Sacedón, Sacedón, Sato, Seo, Shah, Shimizu, Smith, Smith-Garvin, Stewart, Thompson, Varjosalo, Wakelin, Yamane   +72 more
core   +5 more sources

Inflammation and Coagulation are Two Interconnected Pathophysiological Pathways in Atrial Fibrillation Pathogenesis

Journal of Inflammation Research, 2023
Lusine Hazarapetyan,1,2 Parounak H Zelveian,2 Svetlana Grigoryan1,2 1Department of Cardiology, Yerevan State Medical University Named After M. Heratsi, Yerevan, Armenia; 2Scientific Research Institute of Cardiology Named After L Hovhannisyan, Yerevan ...
Hazarapetyan L, Zelveian PH, Grigoryan S
doaj  

Coagulation in Brain Tumors: Biological Basis and Clinical Implications

Frontiers in Neurology, 2019
Cancer patients commonly show abnormal laboratory coagulation tests, indicating a subclinical hypercoagulable condition that contribute to morbidity and mortality.
Chiara Mandoj, Luigi Tomao, Laura Conti
doaj   +1 more source