Results 11 to 20 of about 948,754 (196)

Propofol promotes angiogenesis in rats with postmenopausal osteoporosis [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate the impact of propofol on angiogenesis in postmenopausal osteoporosis (PMOP) rats and the role of Wnt/β-catenin signal pathway in this process. Methods Female Wistar rats were randomly grouped into sham operation group,
ZHAO Xiaoqi, DONG Xin, LIU Cong, REN Pengcheng, ZHANG Liang
doaj   +1 more source

Expression of tissue factor and tissue factor pathway inhibitors during ovulation in rats: a relevance to the ovarian hyperstimulation syndrome

open access: yesReproductive Biology and Endocrinology, 2021
Background Blood coagulation has been associated with ovulation and female infertility. In this study, the expression of the tissue factor system was examined during ovulation in immature rats; the correlation between tissue factor and ovarian ...
You Jee Jang   +6 more
doaj   +1 more source

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]

open access: yes, 2012
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone   +2 more
core   +2 more sources

Tissue Factor Pathway Inhibitor [PDF]

open access: yesEuropean Journal of Biochemistry, 2002
We have analyzed several mathematical models that describe inhibition of the factor VIIa–tissue factor complex (VIIa–TF) by tissue factor pathway inhibitor (TFPI). At the core of these models is a common mechanism of TFPI action suggesting that only the Xa–TFPI complex is the inhibitor of the extrinsic tenase activity.
Debra Hoppensteadt   +2 more
openaire   +3 more sources

Tissue factor pathway inhibitor revisited [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2004
P F, Hjort   +6 more
  +13 more sources

Heparanase and Coagulation–New Insights

open access: yesRambam Maimonides Medical Journal, 2014
Heparanase, a β-D-endoglucuronidase abundant in platelets that was discovered 30 years ago, is an enzyme that cleaves heparan sulfate side chains on the cell surface and in the extracellular matrix. It was later recognized as being a pro-inflammatory and
Yona Nadir
doaj   +1 more source

Heparanase—A Link between Coagulation, Angiogenesis, and Cancer

open access: yesRambam Maimonides Medical Journal, 2012
Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner.
Yona Nadir, Benjamin Brenner
doaj   +1 more source

JNK signalling in cancer: In need of new, smarter therapeutic targets [PDF]

open access: yes, 2013
Copyright © 2013 The British Pharmacological Society. This is the accepted version of the following article: Bubici, C. and Papa, S. (2014), JNK signalling in cancer: in need of new, smarter therapeutic targets.
Adams   +137 more
core   +2 more sources

Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells [PDF]

open access: yes, 2005
A small cell-permeable compound, dehydroxymethylepoxyquinomicin (DHMEQ), does not inhibit phosphorylation and degradation of IκB (inhibitor of nuclear factor-κB [NF-κB]) but selectively inhibits nuclear translocation of activated NF-κB.
Kubota, Tetsuo   +4 more
core   +2 more sources

Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways [PDF]

open access: yes, 2020
Background: Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by upregulating the expression of ...
A Argentaro   +67 more
core   +2 more sources

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