Results 201 to 210 of about 1,251,677 (333)

Befovacimab, an anti-tissue factor pathway inhibitor antibody: Early termination of the multiple-dose, dose-escalating Phase 2 study due to thrombosis. [PDF]

Haemophilia, 2022
Mancuso ME, Ingham SJM, Kunze M.
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Marstacimab for the Treatment of Hemophilia A or B

Biologics: Targets & Therapy
Johnny Mahlangu Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South AfricaCorrespondence: Johnny Mahlangu, Department of Molecular Medicine and Haematology, Faculty of Health ...
Mahlangu J
doaj  

Reassessing the Role of Tissue Factor Pathway Inhibitor 2 in Neoplastic and Non-Neoplastic Lesions. [PDF]

Cancers (Basel)
Kobayashi H, Shigetomi H, Imanaka S.
europepmc   +1 more source

Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle-aged and older adults: A population-based cohort study. [PDF]

Res Pract Thromb Haemost, 2022
Manderstedt E, Lind-Halldén C, Halldén C, Elf J, Svensson PJ, Engström G, Melander O, Baras A, Lotta LA, Zöller B, Regeneron Genetics Center.   +10 more
europepmc   +1 more source

Tissue factor pathway inhibitor and tissue factor in HD and CAPD [PDF]

, 1998
Jolanta Małyszko
openalex   +1 more source

Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE−/− Mice

Circulation, 2015
Daxin Chen, M. Xia, C. Hayford, E. Tham, Vikki Semik, S. Hurst, Ying Chen, Henry H Tam, Jun Pan, Yu-Chieh Wang, Xiao-jie Tan, H. Lan, Huahao Shen, V. Kakkar, Qingbo Xu, J. McVey, A. Dorling   +16 more
semanticscholar   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis. [PDF]

J Gastrointest Oncol
Wang XL, Qin S, Liu L, Jia YQ, Wang Y, Zhou YJ, Ramos-Molina B, Valladares-Ayerbes M, Eidens M, Liu ZZ.   +9 more
europepmc   +1 more source

Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa [PDF]

, 1992
Robin L. Wesselschmidt, K Likert, T Girard, TC Wun, GJ Jr Broze   +4 more
openalex   +1 more source