Results 21 to 30 of about 84,021 (262)

Kind of Sample as Preanalytical Determinant of Matrix Metalloproteinases 2 and 9 and Tissue Inhibitor of Metalloproteinase 2 in Blood [PDF]

open access: yesClinical Chemistry, 1998
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are interesting new diagnostic tools in oncology, liver diseases, and rheumatoid arthritis (1)(2)(3)(4)(5). However, the preanalytical issue of their determination in blood was only recently shown (6).
Jung, K   +6 more
openaire   +3 more sources

Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease [PDF]

open access: yesKorean Journal of Pediatrics, 2010
Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis ...
Ki Wook Yun   +7 more
doaj   +1 more source

An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy [PDF]

open access: yesNephrology Dialysis Transplantation, 2006
High glucose and angiotensin-II (Ang-II) levels are the known important mediators of diabetic nephropathy. However, the effects of these mediators on matrix metalloproteinase-2 (MMP-2) and on tissue inhibitor of metalloproteinase-2 (TIMP-2) in proximal tubule cells have yet to be fully examined within the context of early stage diabetic nephropathy.In ...
Sang Youb, Han   +7 more
openaire   +2 more sources

Role of Oxidative Stress and Genetic Polymorphism of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in COPD

open access: yesChronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, 2023
Article in press withdrawn by publisher.
Poonam, Sangwan   +4 more
openaire   +2 more sources

Relationships between markers of extracellular matrix degradation and systemic inflammatory response among patients with acute myocardial infarction

open access: yesСучасні медичні технології, 2020
Despite all the preventive, diagnostic and therapeutic possibilities of our time, diseases of the circulatory system are the leading causes of death among adult population both in the world and in Ukraine.
E. V. Sid, V. V. Litvinenko
doaj   +1 more source

Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients

open access: yesFolia Histochemica et Cytobiologica, 2012
The positive expression of MMP-2 and TIMP-2 were found in esophageal cancer (EC) tissue and correlated with cancer stage and clinico-pathological features of tumor and patients' survival. However, little is known about serum levels of those proteins in EC patients. The aim of the present study was to investigate the diagnostic significance of MMP-2 and
Magdalena, Groblewska   +5 more
openaire   +3 more sources

Matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expression is not regulated by norgestimate or norelgestromin

open access: yesGynecological Endocrinology, 2004
Steroid hormones regulate endometrial expression of matrix metalloproteinases (MMPs) and their inhibitors. Synthetic progestins are widely used in oral contraceptives and for hormone replacement therapy. To assess whether the synthetic progestins norgestimate and its derivative norelgestromin (17-deacetylnorgestimate) modulate the expression of MMPs ...
Prifti, S   +4 more
openaire   +3 more sources

Immunohistochemical Correlation of Matrix Metalloproteinase-2 and Tissue Inhibitors of Metalloproteinase-2 in Tobacco Associated Epithelial Dysplasia [PDF]

open access: yesDisease Markers, 2014
Aim. To study the immunohistochemical expression of matrix metalloproteinase and tissue inhibitors of matrix metalloproteinase-2 in different histological grades of tobacco associated epithelial dysplasia and correlate the association between these proteases.
Dipshikha Bajracharya   +4 more
openaire   +2 more sources

Matrix metalloproteinase‐2 promoter and tissue inhibitor of metalloproteinase‐2 gene polymorphisms in non‐Hodgkin's lymphoma [PDF]

open access: yesInternational Journal of Cancer, 2011
AbstractSingle nucleotide polymorphisms in the promoter regions of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMP) genes are associated with an adverse outcome in some cancers. We examined three polymorphisms: −1306C/T and −735C/T in MMP‐2 and −418G/C in the TIMP‐2 gene, using chain reaction restriction fragment ...
Lan-Ping, Diao   +8 more
openaire   +2 more sources

The Distribution of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-4 in Psoriatic Skin

open access: yesBritish Journal of Medicine and Medical Research, 2015
Aims: To evaluate the appearance and distribution of matrix metalloproteinase-2 (MMP-2), tissue inhibitor of metalloproteinase-2 (TIMP-2) and tissue inhibitor of metalloproteinase-4 (TIMP-4) in lesional skin biopsies of psoriasis patients. Study Design: Observational study.
Elga Sidhom, Mara Pilmane, Janis Kisis
openaire   +1 more source

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