Results 31 to 40 of about 84,021 (262)

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis

BMC Cancer, 2020
Background Expression of matrix metalloproteases 2, 9 and 14 (MMP-2, MMP-9, MMP-14), tissue inhibitors of metalloprotease 1 and 2 (TIMP-1, TIMP-2) and vascular endothelial growth factor A (VEGF-A) is involved in tumor invasion and metastasis via ...
Jordana Maria Azevedo Martins, Silvia Helena Rabelo-Santos, Maria Cristina do Amaral Westin, Luiz Carlos Zeferino   +3 more
doaj   +1 more source

Neutrophil Adhesion and the Release of the Free Amino Acid Hydroxylysine

Cells, 2021
During infection or certain metabolic disorders, neutrophils can escape from blood vessels, invade and attach to other tissues. The invasion and adhesion of neutrophils is accompanied and maintained by their own secretion.
Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Marina V. Serebryakova, Ekaterina A. Golenkina, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’ina   +7 more
doaj   +1 more source

Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis [PDF]

International Journal of Cancer, 1997
Degradation of basement membranes is a key step in tumoral invasion, mainly mediated by matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). Since the liver is a main target for metastases from gastrointestinal adenocarcinoma, we have investigated MMP2 and TIMP2 expression by RT-PCR, in situ hybridization and zymography in the liver of ...
N, Théret, O, Musso, J P, Campion, B, Turlin, O, Loréal, A, L'Helgoualc'h, B, Clément   +6 more
openaire   +2 more sources

ELISA study of matrix metalloproteinases 2, 7, 9 and their type 2 tissue inhibitor in the tumors of gastric cancer patients: clinical and pathologic correlations

Alʹmanah Kliničeskoj Mediciny, 2018
Background: Over the last 10 years the incidence of gastric cancer has declined significantly. Nevertheless, it remains one of the most prevalent malignancies both in Russia and worldwide.
E. S. Gershtein, A. A. Ivannikov, V. L. Chang, N. A. Ognerubov, М. M. Davydov, I. S. Stilidi, N. E. Kushlinskii   +6 more
doaj   +1 more source

Expression of cellular adherent and invasive molecules in recurrent ovarian endometriosis

Journal of International Medical Research, 2020
Objective This study aimed to examine expression of cellular adhesion molecules and metalloproteinases of the extracellular matrix in ectopic endometrium for evaluating their roles in recurrence of endometriosis.
Tingting Wu, Rongyan Zhang, Qiaoying Jiang, Zhi Li, Ruijin Wu   +4 more
doaj   +1 more source

Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population

BMJ Open Diabetes Research & Care, 2020
IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
doaj   +1 more source

Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]

Iranian Journal of Otorhinolaryngology, 2019
Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk, Piotr Sawicki, Lukasz Szylberg, Magdalena Bodnar, Andrzej Marszalek   +4 more
doaj   +1 more source

MMP-2 and TIMP-2 in patients with heart failure and chronic kidney disease

Open Medicine, 2018
The aim of the study was to assess MMP-2 (matrix metalloproteinase-2) and TIMP-2 (tissue inhibitor of metalloproteinase-2) serum levels in patients with diverse types of heart failure (HF) and chronic kidney disease (CKD).
Kobusiak-Prokopowicz Malgorzata, Krzysztofik Justyna, Kaaz Konrad, Jolda-Mydlowska Beata, Mysiak Andrzej   +4 more
doaj   +1 more source

Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma

Frontiers in Immunology, 2019
Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Kentaro Fujiwara, Tomohito Okano, Hajime Fujimoto, Kentaro Asayama, Atsuro Takeshita, Atsuro Takeshita, Taro Yasuma, Taro Yasuma, Kota Nishihama, Ryo Inoue, Liqiang Qin, Yoshiyuki Takei, Osamu Taguchi, Esteban C. Gabazza   +17 more
doaj   +1 more source

Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion

Endocrine Oncology
Objective: To evaluate the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) in pituitary tumors and investigate their correlation with circulating plasma proteins and cavernous sinus invasion ...
Ane Caroline Thé B Freire, Raquel S Jallad, Rafael L Batista, Andrea Glezer, Marcio C Machado, Gilberto Ochman, Valter A Cescato, Malebranche Berardo Carneiro Cunha Neto, Fernando P Frassetto, Raphael S S de Medeiros, Ericka B Trarbach   +10 more
doaj   +1 more source