Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 [PDF]
Journal of Biomedical Science, 2022 Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported.
Shan-Ying Wu +8 more
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Roles of Tissue Inhibitor of Metalloproteinase-1 in Severe Asthma. [PDF]
Allergy Asthma Immunol Res, 2023 https://e-aair.org A wide array of inflammatory cytokines and mediators play roles in immune response and chronic inflammation in severe asthma (SA).
Kim SH.
europepmc +4 more sources
Tissue Inhibitor of Metalloproteinase-1 Is Increased in Chagasic Cardiomyopathy. [PDF]
Am J Trop Med Hyg, 2021 ABSTRACT. Chagas disease (CD) mainly conveys stroke risk through structural cardiac disease. However, stroke and cognitive impairment are seen in CD independently of cardiac disease severity. Chronic inflammation may be an explanation for this association, because inflammation plays an important role in the pathogenesis of acute ischemic stroke and ...
Garcia KO +17 more
europepmc +5 more sources
Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury. [PDF]
J Int Med Res, 2020 Objective This study aimed to examine the changes and significance of matrix metalloproteinase 9 (MMP9), MMP2, tissue inhibitor of metalloproteinase 1 (TIMP1), and TIMP2 in rats with lipopolysaccharide (LPS)-induced acute lung injury (ALI).
Chen G, Ge D, Zhu B, Shi H, Ma Q.
europepmc +2 more sources
Relationship between Circulating Serpina3g, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinase-1 and -2 with Chronic Obstructive Pulmonary Disease Severity [PDF]
Biomolecules, 2019 Chronic obstructive pulmonary disease (COPD) is influenced by genetic and environmental factors. A protease-antiprotease imbalance has been suggested as a possible pathogenic mechanism for COPD.
Pelin Uysal, Hafize Uzun
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Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Endometriosis Menstrual Blood [PDF]
Diagnostics, 2020 Endometriosis is a gynecological disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Remodeling of the extracellular matrix (ECM) is a prerequisite for tissue implantation. The presence of matrix metalloproteinase
Tita Husnitawati Madjid +3 more
doaj +2 more sources
Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline. [PDF]
Int J Chron Obstruct Pulmon Dis, 2018 Background Airway hyperresponsiveness (AHR) is associated with airway inflammation and a rapid decline in lung function and is a predictor of future risk of COPD among smokers.
Lo CY +8 more
europepmc +2 more sources
Expression of collagenases (matrix metalloproteinase-1, 8, 13) and tissue inhibitor of metalloproteinase-1 of retrodiscal tissue in temporomandibular joint disorder patients. [PDF]
J Korean Assoc Oral Maxillofac Surg, 2018 Objectives The aim of this study was to reveal how collagenases (matrix metalloproteinase [MMP]-1, 8, 13) and tissue inhibitor of metalloproteinase 1 (TIMP-1) are expressed in immunohistochemistry of retrodiscal tissue in temporomandibular joint disorder
Gho WG, Choi Y, Park KH, Huh JK.
europepmc +2 more sources
Tissue inhibitor of metalloproteinase-1 (TIMP-1) as a prognostic biomarker in gastrointestinal cancer: a meta-analysis [PDF]
PeerJ, 2021 Background Tissue inhibitor of metalloproteinase 1 (TIMP-1) has recently been shown to be dependent on or independent of Matrix metalloproteinases (MMPs) in its roles in tumorigenesis and progression.
Lili Qin +6 more
doaj +3 more sources
Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population [PDF]
BMJ Open Diabetes Research & Care, 2020 IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
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