Prognostic Significance of Tissue Inhibitor of Metalloproteinase-1 in Breast Cancer [PDF]
International Journal of Breast Cancer, 2012 Introduction. Despite advances in breast cancer systemic treatment, new prognostic and predictive factors are still needed. Tissue inhibitor of metalloproteinase-1 (TIMP-1), a physiologic inhibitor of matrix metalloproteinases (MMPs), can act in both pro-
Arunee Dechaphunkul +6 more
doaj +5 more sources
Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2012 Tissue inhibitor of metalloproteinases 1 (TIMP-1) is a matrix metalloproteinase (MMP)-independent regulator of growth and apoptosis in various cell types.
Virginia Egea +7 more
semanticscholar +3 more sources
Tissue inhibitor of metalloproteinase-1 and interleukin-10 in serum from naïve and scrapie infected sheep [PDF]
Veterinary and Animal Science, 2019 Tissue inhibitor of metalloproteinase-1 (TIMP-1) and interleukin-10 (IL-10) were identified as potential biomarkers for ovine scrapie in a mouse model.
Marta G. Silva +4 more
doaj +2 more sources
Saudi Dental Journal, 2014 Background: Matrix metalloproteinase-1 (MMP-1) is a member of a family of enzymes that can degrade most extracellular matrix macromolecules. Extracellularly, MMPs are controlled by tissue inhibitors of metalloproteinases (TIMPs) and by mechanisms of pro ...
Pallavi S. Ghodpage +3 more
doaj +3 more sources
Tissue Inhibitor of Metalloproteinase 1 Measurement [PDF]
Definitions, 2020 semanticscholar +2 more sources
Prognostic value of determination of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 in follicular fluid in patients in vitro fertilization programs [PDF]
Гинекология, 2021 Aim. To determine the prognostic significance of matrix metalloproteinase-1 (MMP-1) and tissue metalloproteinase-1 inhibitor (TIMP-1) in the follicular fluid (FF) in patients with infertility to improve the effectiveness of in vitro fertilization (IVF ...
Olga A. Marinova +2 more
doaj +1 more source
Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite [PDF]
FEBS Letters, 1996 Peroxynitrate (ONOO−) has recently been implicated in connective tissue destruction in vivo. We have studied the effect of ONOO− on the activity of tissue inhibitor of metalloproteinase‐1 (TIMP‐1) in vitro. The inactivation of TIMP‐1 by ONOO− was dose dependent with 50 μM ONOO− reducing the inhibitory activity of TIMP‐1 towards gelatinase‐A by 50 ...
Frears, Emma R. +4 more
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Tissue Inhibitor of Metalloproteinase 1 Regulates Resistance to Infection [PDF]
Infection and Immunity, 2005 ABSTRACT Tissue inhibitor of metalloproteinase 1 (TIMP-1)-deficient mice are resistant to Pseudomonas aeruginosa corneal infections. Corneas healed completely in TIMP-1-deficient mice, and infections were cleared faster in TIMP-1-deficient mice than in wild-type littermates.
Marie Mei, Lee +7 more
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Journal of Advanced Biotechnology and Experimental Therapeutics, 2023 SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael +2 more
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Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition. [PDF]
Cardiology, 2015 Matrix metalloproteinases (MMPs) are a family of zinc-dependent enzymes, which include 25 current members. MMPs degrade structural components of extracellular matrix and process bioactive molecules including cytokines, chemokines, and growth factors [1].
Lindsey ML, Yabluchanskiy A, Ma Y.
europepmc +4 more sources